199522-66-2

Basic information

• Product Name: N1-(5-Bromopyrid-2-yl)ethane-1,2-diamine
• Synonyms: N1-(5-Bromopyrid-2-yl)ethane-1,2-diamine;1,2-Ethanediamine, N1-(5-bromo-2-pyridinyl)-;N1-(5-Bromo-2-pyridinyl)-1,2-ethanediamine;N1-(5-Bromopyrid-2-yl)
• CAS NO: 199522-66-2
• Molecular Formula: C₇H₁₀BrN₃
• Molecular Weight: 216.09
• Product Categories: pharmacetical;amine| alkyl bromide
• Mol File: 199522-66-2.mol
• Article Data: 7

Chemical Properties

• Boiling Point: 327.529°C at 760 mmHg
• Flash Point: 151.884°C
• Appearance: /
• Density: 1.56g/cm³
• Vapor Pressure: 0mmHg at 25°C
• Refractive Index: 1.639
• Storage Temp.: Keep in dark place,Inert atmosphere,Room temperature
• PKA: 9.06±0.10(Predicted)
• CAS DataBase Reference: N1-(5-Bromopyrid-2-yl)ethane-1,2-diamine(CAS DataBase Reference)
• NIST Chemistry Reference: N1-(5-Bromopyrid-2-yl)ethane-1,2-diamine(199522-66-2)
• EPA Substance Registry System: N1-(5-Bromopyrid-2-yl)ethane-1,2-diamine(199522-66-2)

Safety Data

• Hazardous Substances Data: 199522-66-2(Hazardous Substances Data)

Usage

General Description

N1-(5-Bromopyrid-2-yl)ethane-1,2-diamine is a chemical compound with the molecular formula C7H11BrN3. It is a derivative of ethane-1,2-diamine, with a pyridine ring substituted with a bromine atom and an ethylamine group. N1-(5-Bromopyrid-2-yl)ethane-1,2-diamine is primarily used in organic synthesis and pharmaceutical research as a building block and intermediate for the synthesis of various biologically active compounds. Its potential applications include the development of antiviral and anticancer agents, as well as other therapeutic drugs. N1-(5-Bromopyrid-2-yl)ethane-1,2-diamine is a valuable chemical in the field of medicinal chemistry and drug discovery.

InChI:InChI=1/C7H10BrN3/c8-6-1-2-7(11-5-6)10-4-3-9/h1-2,5H,3-4,9H2,(H,10,11)

Upstream product

• 624-28-2 2,5-dibromopyridine 
• 107-15-3 ethylenediamine 

Downstream Products

• 866930-72-5 tert-butyl {2-[(5-bromopyridin-2-yl)amino]ethyl}carbamate 
• 1401342-14-0 C₂₂H₂₅FN₆O₃ 
• 1401342-13-9 C₂₃H₂₃FN₆O₃ 
• 1401342-12-8 C₂₂H₂₃FN₆O₅ 
• 1401342-11-7 C₂₀H₂₁FN₆O₃*ClH 
• 1401342-10-6 C₂₁H₂₁FN₆O₄ 

Relevant articles and documents

BIARYL MONOBACTAM COMPOUNDS AND METHODS OF USE THEREOF FOR THE TREATMENT OF BACTERIAL INFECTIONS

The present invention relates to biaryl monobactam compounds of Formula I: and pharmaceutically acceptable salts thereof, wherein X, Y, Z, A1, Q, A2, M, W, RX and Rz are as defined herein. The present invention also relates to compositions which comprise a biaryl monobactam compound of the invention or a pharmaceutically acceptable salt therof, and a pharmaceutically acceptable carrier. The invention further relates to methods for treating a bacterial infection comprising administering to the patient a therapeutically effective amount of a compound of the invention, either alone or in combination with a therapeutically effective amount of a second beta-lactam antibiotic.

NOVEL OXAZOLIDINONE DERIVATIVE AND MEDICAL COMPOSITION CONTAINING SAME

Disclosed is a novel oxazolidinone derivative represented by Formula 1 above, in particular, a novel oxazolidinone compound having a cyclic amidoxime or cyclic amidrazone group. In Formula 1, R and Q are the same as defined in the detailed description. In addition, disclosed is a pharmaceutical composition for an antibiotic which includes the novel oxazolidinone derivative of Formula 1, a prodrug thereof, a hydrate thereof, a solvate thereof, an isomer thereof, or a pharmaceutically acceptable salt thereof as an active ingredient. The novel oxazolidinone derivative, the prodrug thereof, the hydrate thereof, the solvate thereof, the isomer thereof, and the pharmaceutically acceptable salt thereof have broad antibacterial spectrum against resistant bacteria, low toxicity and strong antibacterial effects against Gram-positive and Gram-negative bacteria and thus may be effectively used as antibiotics.

Inhibitors of histone deacetylase

The invention relates to the inhibition of histone deacetylase. The invention provides compounds and methods for inhibiting histone deacetylase enzymatic activity. The invention also provides compositions and methods for treating cell proliferative diseases and conditions.