N-(6-((4-methyl-2-oxo-2H-chromen-7-yl)oxy)pyridin-3-yl)cyclohexanecarboxamide

Base Information

Chemical Name:N-(6-((4-methyl-2-oxo-2H-chromen-7-yl)oxy)pyridin-3-yl)cyclohexanecarboxamide
CAS No.:1420160-81-1
Molecular Formula:C₂₂H₂₂N₂O₄
Molecular Weight:378.428
Hs Code.:

Synonyms:N-(6-((4-methyl-2-oxo-2H-chromen-7-yl)oxy)pyridin-3-yl)cyclohexanecarboxamide

Suppliers and Price of N-(6-((4-methyl-2-oxo-2H-chromen-7-yl)oxy)pyridin-3-yl)cyclohexanecarboxamide

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

Total 0 raw suppliers

Chemical Property of N-(6-((4-methyl-2-oxo-2H-chromen-7-yl)oxy)pyridin-3-yl)cyclohexanecarboxamide

Chemical Property:

Purity/Quality:

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:

Useful:

Technology Process of N-(6-((4-methyl-2-oxo-2H-chromen-7-yl)oxy)pyridin-3-yl)cyclohexanecarboxamide

There total 4 articles about N-(6-((4-methyl-2-oxo-2H-chromen-7-yl)oxy)pyridin-3-yl)cyclohexanecarboxamide which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 83.4%

: 954584-43-1
7-(5-aminopyridin-2-yloxy)-4-methyl-2H-chromen-2-one

: 98-89-5
Cyclohexanecarboxylic acid

: 1420160-81-1
N-(6-((4-methyl-2-oxo-2H-chromen-7-yl)oxy)pyridin-3-yl)cyclohexanecarboxamide

Guidance literature:: With dmap; 1-ethyl-(3-(3-dimethylamino)propyl)-carbodiimide hydrochloride; In dichloromethane; at 20 ℃; for 12h;
DOI:10.1007/s00044-013-0470-2

Reference yield:

: 90-33-5,79566-13-5
7-hydroxy-4-methyl-chromen-2-one

: 1420160-81-1
N-(6-((4-methyl-2-oxo-2H-chromen-7-yl)oxy)pyridin-3-yl)cyclohexanecarboxamide

Guidance literature:: Multi-step reaction with 3 steps

1: potassium carbonate / acetonitrile / 5.5 h / 20 °C / Reflux

2: palladium on activated charcoal; hydrogen / ethanol / 2 h

3: dmap; 1-ethyl-(3-(3-dimethylamino)propyl)-carbodiimide hydrochloride / dichloromethane / 12 h / 20 °C

With dmap; palladium on activated charcoal; hydrogen; potassium carbonate; 1-ethyl-(3-(3-dimethylamino)propyl)-carbodiimide hydrochloride; In ethanol; dichloromethane; acetonitrile;
DOI:10.1007/s00044-013-0470-2

Reference yield:

: 108-46-3
recorcinol

: 1420160-81-1
N-(6-((4-methyl-2-oxo-2H-chromen-7-yl)oxy)pyridin-3-yl)cyclohexanecarboxamide

Guidance literature:: Multi-step reaction with 4 steps

1: sulfuric acid / 8 h / Cooling with ice

2: potassium carbonate / acetonitrile / 5.5 h / 20 °C / Reflux

3: palladium on activated charcoal; hydrogen / ethanol / 2 h

4: dmap; 1-ethyl-(3-(3-dimethylamino)propyl)-carbodiimide hydrochloride / dichloromethane / 12 h / 20 °C

With dmap; sulfuric acid; palladium on activated charcoal; hydrogen; potassium carbonate; 1-ethyl-(3-(3-dimethylamino)propyl)-carbodiimide hydrochloride; In ethanol; dichloromethane; acetonitrile;
DOI:10.1007/s00044-013-0470-2