2-(4-chlorophenyl)acetaldehyde oxime

Base Information

• Chemical Name: 2-(4-chlorophenyl)acetaldehyde oxime
• CAS No.: 4410-18-8
• Molecular Formula: C₈H₈ClNO
• Molecular Weight: 169.611
• Mol file: 4410-18-8.mol

Synonyms:2-(4-chlorophenyl)acetaldehyde oxime

Chemical Property of 2-(4-chlorophenyl)acetaldehyde oxime

Chemical Property:

Purity/Quality:

95% ^*data from raw suppliers

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

Useful:

Technology Process of 2-(4-chlorophenyl)acetaldehyde oxime

There total 7 articles about 2-(4-chlorophenyl)acetaldehyde oxime which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 85.0%

1-chloro-4-(2-nitrovinyl)benzene (706-07-0,5153-70-8) → 2-(4-chlorophenyl)acetaldehyde oxime (4410-18-8)

Guidance literature:

With sulfuric acid; In water; isopropyl alcohol; at 10 - 15 ℃; electrolysis;

Reference yield: 79.0%

1-chloro-4-(2-nitroethyl)benzene (60947-43-5) → 2-(4-chlorophenyl)acetaldehyde oxime (4410-18-8)

Guidance literature:

With maghemite; methylhydrazine; In ethanol; at 60 ℃; for 12h; chemoselective reaction; Sealed tube; Inert atmosphere;

DOI:10.1002/chem.201504685

Reference yield: 51.0%

1-chloro-4-(2-nitroethyl)benzene (60947-43-5) → 2-(4-chlorophenyl)acetaldehyde oxime (4410-18-8) + p-chlorobenzyl cyanide (140-53-4)

Guidance literature:

With trichlorosilane; N-ethyl-N,N-diisopropylamine; In dichloromethane; at -20 ℃; for 3h; Reagent/catalyst; Inert atmosphere;

DOI:10.1002/chem.202100889

upstream raw materials:

1-chloro-4-(2-nitrovinyl)benzene

4-chlorobenzaldehyde

1-chloro-4-(2-nitroethyl)benzene

Downstream raw materials:

N.N'-Di--thioharnstoff

5-(4-chloro-phenyl)-thiazolidine-2-thione

Refernces

• 1、 Papadas, Ioannis T.,Fountoulaki, Stella,Lykakis, Ioannis N.,Armatas, Gerasimos S.. "Controllable Synthesis of Mesoporous Iron Oxide Nanoparticle Assemblies for Chemoselective Catalytic Reduction of Nitroarenes". . p. 4600 - 4607. Retrieved 2016/03/22.
• 2、 Shono, Tatsuya,Hamaguchi, Hiroshi,Mikami, Hiroshi,Nogusa, Hideo,Kashimura, Shigenori. "Electroorganic Chemistry. 59. Electroreductive Synthesis of Oximes from Nitro Olefins". . p. 2103 - 2105. Retrieved 2007/10/02.