5-bromo-7-nitro-1H-indole

Base Information

Chemical Name:5-bromo-7-nitro-1H-indole
CAS No.:165669-16-9
Molecular Formula:C8H5 Br N2 O2
Molecular Weight:241.044
Hs Code.:2933990090
European Community (EC) Number:681-336-0
DSSTox Substance ID:DTXSID70355690
Nikkaji Number:J767.734K
Wikidata:Q82134719
Mol file:165669-16-9.mol

Synonyms:5-bromo-7-nitro-1H-indole;5-bromo-7-nitroindole;165669-16-9;MFCD00619260;SCHEMBL1983087;1H-Indole, 5-bromo-7-nitro-;AMY7398;DTXSID70355690;WERRDKWLHFDNTO-UHFFFAOYSA-N;AKOS005206919;SB15214;DS-16482;SY039735;CS-0041609;FT-0620151;B-8955;A882383;SR-01000317397;SR-01000317397-1;[5-[[4-(Acetylamino)phenyl]thio]-1H-benzimidazol-2-yl]-carbamic acid methyl ester

Suppliers and Price of 5-bromo-7-nitro-1H-indole

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

SynQuest Laboratories
5-Bromo-7-nitro-1H-indole
10 g
$ 1085.00

SynQuest Laboratories
5-Bromo-7-nitro-1H-indole
1 g
$ 197.00

SynQuest Laboratories
5-Bromo-7-nitro-1H-indole
5 g
$ 628.00

Matrix Scientific
5-Bromo-7-nitro-1H-indole
1g
$ 282.00

Crysdot
5-Bromo-7-nitro-1H-indole 98%
5g
$ 416.00

Chemenu
5-Bromo-7-nitro-1H-indole 95%+
5g
$ 393.00

Chemenu
5-Bromo-7-nitro-1H-indole 95%+
1g
$ 143.00

Biosynth Carbosynth
5-Bromo-7-Nitroindole
500 mg
$ 100.00

Biosynth Carbosynth
5-Bromo-7-Nitroindole
250 mg
$ 62.50

Biosynth Carbosynth
5-Bromo-7-Nitroindole
1 g
$ 161.00

Total 19 raw suppliers

Chemical Property of 5-bromo-7-nitro-1H-indole

Chemical Property:

Vapor Pressure:2.57E-06mmHg at 25°C
Melting Point:213-215°C
Refractive Index:1.747
Boiling Point:402.3°Cat760mmHg
PKA:13.00±0.30(Predicted)
Flash Point:197.1°C
PSA：61.61000
Density:1.855g/cm³
LogP:3.36180
Storage Temp.:Inert atmosphere,Room Temperature
Water Solubility.:Insoluble in water.
XLogP3:3.3
Hydrogen Bond Donor Count:1
Hydrogen Bond Acceptor Count:2
Rotatable Bond Count:0
Exact Mass:239.95344
Heavy Atom Count:13
Complexity:219

Purity/Quality:

97% ^*data from raw suppliers

5-Bromo-7-nitro-1H-indole ^*data from reagent suppliers

Safty Information:

Pictogram(s):
Hazard Codes:
Statements: 68
Safety Statements: S22:Do not inhale dust.; S36/37:Wear suitable protective clothing and gloves.;

MSDS Files:

Useful:

Canonical SMILES:C1=CNC2=C(C=C(C=C21)Br)[N+](=O)[O-]
Uses 5-Bromo-7-nitroindole is used in gas chromatography analysis. It is also used as pharmaceutical and medical intermediate.

Technology Process of 5-bromo-7-nitro-1H-indole

There total 2 articles about 5-bromo-7-nitro-1H-indole which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

: 62368-07-4
1-acetyl-5-bromo-7-nitro-2,3-dihydro-1H-indole

: 165669-16-9
5-Bromo-7-nitroindole

Guidance literature:: Multi-step reaction with 2 steps

1: sodium hydroxide / methanol; tetrahydrofuran / 0.5 h / 0 - 20 °C

2: manganese(IV) oxide / dichloromethane / 12 h / 0 - 20 °C / Inert atmosphere

With manganese(IV) oxide; sodium hydroxide; In tetrahydrofuran; methanol; dichloromethane;
DOI:10.1002/chem.202000579

Reference yield:

: 22190-38-1
5-bromo-N-acetylindoline

: 165669-16-9
5-Bromo-7-nitroindole

Guidance literature:: Multi-step reaction with 3 steps

1: trifluoroacetic acid; sodium nitrate / 0.5 h / 0 - 20 °C

2: sodium hydroxide / methanol; tetrahydrofuran / 0.5 h / 0 - 20 °C

3: manganese(IV) oxide / dichloromethane / 12 h / 0 - 20 °C / Inert atmosphere

With manganese(IV) oxide; sodium nitrate; trifluoroacetic acid; sodium hydroxide; In tetrahydrofuran; methanol; dichloromethane;
DOI:10.1002/chem.202000579

Reference yield: 50.46%

: 117-80-6
2,3-Dichloro-1,4-naphthoquinone

: 98-68-0
4-methoxy-phenyl-sulphonyl chloride

: 165669-16-9
5-Bromo-7-nitroindole

: 2-chloro-3-((1-((4-methoxyphenyl)sulfonyl)indolin-7-yl)amino)naphthalene-1,4-dione

Guidance literature:: 4-methoxy-phenyl-sulphonyl chloride; 5-Bromo-7-nitroindole; With pyridine; Reflux;

With hydrogen; In methanol; under 2068.65 Torr;

2,3-Dichloro-1,4-naphthoquinone; In ethanol; for 72h; Reflux;