N¹-(quinolin-6-yl)-N²-(4-acetoamidobenzene-1-sulfonyl)-3-(5-methyl-2,4-dioxo-3,4-dihydropyrimidin-1(2H)-yl)propanamidine

Base Information

• Chemical Name: N¹-(quinolin-6-yl)-N²-(4-acetoamidobenzene-1-sulfonyl)-3-(5-methyl-2,4-dioxo-3,4-dihydropyrimidin-1(2H)-yl)propanamidine
• CAS No.: 1422277-75-5
• Molecular Formula: C₂₅H₂₄N₆O₅S
• Molecular Weight: 520.569

Synonyms:N¹-(quinolin-6-yl)-N²-(4-acetoamidobenzene-1-sulfonyl)-3-(5-methyl-2,4-dioxo-3,4-dihydropyrimidin-1(2H)-yl)propanamidine

Chemical Property of N¹-(quinolin-6-yl)-N²-(4-acetoamidobenzene-1-sulfonyl)-3-(5-methyl-2,4-dioxo-3,4-dihydropyrimidin-1(2H)-yl)propanamidine

Chemical Property:

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Technology Process of N¹-(quinolin-6-yl)-N²-(4-acetoamidobenzene-1-sulfonyl)-3-(5-methyl-2,4-dioxo-3,4-dihydropyrimidin-1(2H)-yl)propanamidine

There total 1 articles about N¹-(quinolin-6-yl)-N²-(4-acetoamidobenzene-1-sulfonyl)-3-(5-methyl-2,4-dioxo-3,4-dihydropyrimidin-1(2H)-yl)propanamidine which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 54.0%

6-aminoquinoline (580-15-4) + 4-acetamidobenzenesulfonyl azide (2158-14-7) + N-1-propargylthymine (198827-85-9) → N1-(quinolin-6-yl)-N2-(4-acetoamidobenzene-1-sulfonyl)-3-(5-methyl-2,4-dioxo-3,4-dihydropyrimidin-1(2H)-yl)propanamidine (1422277-75-5) + p-acetylaminobenzenesulfonamide (121-61-9)

Guidance literature:

With copper(l) iodide; In tetrahydrofuran; at 25 ℃; for 24h;

DOI:10.5562/cca2198

upstream raw materials:

6-aminoquinoline

4-acetamidobenzenesulfonyl azide

N-1-propargylthymine

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