dimethyl 1α,3-dimethyl-5β-phenyl-8-<(trimethylsilyl)methyl>-2-azabicyclo<2.2.2>oct-2-ene-4,6α-dicarboxylate

Base Information

• Chemical Name: dimethyl 1α,3-dimethyl-5β-phenyl-8-<(trimethylsilyl)methyl>-2-azabicyclo<2.2.2>oct-2-ene-4,6α-dicarboxylate
• CAS No.: 105335-61-3
• Molecular Formula: C₂₃H₃₃NO₄Si
• Molecular Weight: 415.605
• Mol file: 105335-61-3.mol

Synonyms:dimethyl 1α,3-dimethyl-5β-phenyl-8-<(trimethylsilyl)methyl>-2-azabicyclo<2.2.2>oct-2-ene-4,6α-dicarboxylate

Chemical Property of dimethyl 1α,3-dimethyl-5β-phenyl-8-<(trimethylsilyl)methyl>-2-azabicyclo<2.2.2>oct-2-ene-4,6α-dicarboxylate

Chemical Property:

Purity/Quality:

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

Useful:

Technology Process of dimethyl 1α,3-dimethyl-5β-phenyl-8-<(trimethylsilyl)methyl>-2-azabicyclo<2.2.2>oct-2-ene-4,6α-dicarboxylate

There total 2 articles about dimethyl 1α,3-dimethyl-5β-phenyl-8-<(trimethylsilyl)methyl>-2-azabicyclo<2.2.2>oct-2-ene-4,6α-dicarboxylate which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 71.0%

dimethyl 4-phenyl-1,4-dihydro-2,6-dimethylpyridine-3,5-dicarboxylate (70677-78-0,103183-96-6,161838-96-6,192931-34-3) → dimethyl 4-phenyl-2,6-dimethyl-3,5-pyridinedicarboxylate (77234-00-5) + dimethyl 1α,3-dimethyl-5β-phenyl-8-<(trimethylsilyl)methyl>-2-azabicyclo<2.2.2>oct-2-ene-4,6α-dicarboxylate (105335-61-3)

Guidance literature:

With titanium tetrachloride; allyl-trimethyl-silane; In chloroform; at 0 - 10 ℃; for 3h;

DOI:10.1021/jo00382a030

Reference yield: 71.0%

dimethyl 4-phenyl-1,4-dihydro-2,6-dimethylpyridine-3,5-dicarboxylate (70677-78-0,103183-96-6,161838-96-6,192931-34-3) + allyl-trimethyl-silane (762-72-1) → dimethyl 4-phenyl-2,6-dimethyl-3,5-pyridinedicarboxylate (77234-00-5) + dimethyl 1α,3-dimethyl-5β-phenyl-8-<(trimethylsilyl)methyl>-2-azabicyclo<2.2.2>oct-2-ene-4,6α-dicarboxylate (105335-61-3)

Guidance literature:

With titanium tetrachloride; In chloroform; at 0 - 10 ℃; for 3h; Mechanism; other dienes: var. Lewis acids;

DOI:10.1021/jo00382a030

upstream raw materials:

dimethyl 4-phenyl-1,4-dihydro-2,6-dimethylpyridine-3,5-dicarboxylate

allyl-trimethyl-silane