thioctic acid amide

Base Information

Chemical Name:thioctic acid amide
CAS No.:165171-77-7
Molecular Formula:C₈H₁₅NOS₂
Molecular Weight:205.345
Hs Code.:
Mol file:165171-77-7.mol

Synonyms:1,2-Dithiolane-3-pentanamide,(S)- (9CI)

Suppliers and Price of thioctic acid amide

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

Total 3 raw suppliers

Chemical Property of thioctic acid amide

Chemical Property:

Boiling Point:399.2±11.0 °C(Predicted)
PKA:16.59±0.40(Predicted)
PSA：0.00000
Density:1.169±0.06 g/cm3(Predicted)
LogP:0.00000

Purity/Quality:: 98%Min ^*data from raw suppliers

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:

Useful:

Technology Process of thioctic acid amide

There total 7 articles about thioctic acid amide which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 93.0%

: 40846-94-4
thioctic acid-N-hydroxysuccinimide ester

: 940-69-2,165171-77-7,3206-73-3
lipoamide

Guidance literature:: With ammonium hydroxide; In dichloromethane; acetonitrile; at 20 ℃; for 1h; Inert atmosphere;
DOI:10.1016/j.tetlet.2012.08.150

Reference yield: 85.0%

: 1115175-97-7
2,5-dioxopyrrolidin-1-yl 5-(1,2-dithiolan-3-yl)pentanoate

: 165171-77-7,3206-73-3
α-lipoic amide

Guidance literature:: With ammonia; In dichloromethane; at 20 ℃; Cooling with acetone-dry ice;

Reference yield: 34.0%

: 1077-28-7,62-46-4
Thioctic acid

: 940-69-2,165171-77-7,3206-73-3
lipoamide

Guidance literature:: With ammonium hydroxide; immobilized Candida antarctica Lipase B; In 1,4-dioxane; water; at 50 ℃; for 72h; Reagent/catalyst; Sealed tube; Enzymatic reaction;
DOI:10.1016/j.tetlet.2018.04.049