(1R,2S,5R)-2-(4-Benzyloxy-3,5-dimethoxy-phenyl)-5-(3,4,5-trimethoxy-phenyl)-cyclopentanol

Base Information

Chemical Name:(1R,2S,5R)-2-(4-Benzyloxy-3,5-dimethoxy-phenyl)-5-(3,4,5-trimethoxy-phenyl)-cyclopentanol
CAS No.:143814-95-3
Molecular Formula:C₂₉H₃₄O₇
Molecular Weight:494.585
Hs Code.:

Synonyms:(1R,2S,5R)-2-(4-Benzyloxy-3,5-dimethoxy-phenyl)-5-(3,4,5-trimethoxy-phenyl)-cyclopentanol

Suppliers and Price of (1R,2S,5R)-2-(4-Benzyloxy-3,5-dimethoxy-phenyl)-5-(3,4,5-trimethoxy-phenyl)-cyclopentanol

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Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

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Chemical Property of (1R,2S,5R)-2-(4-Benzyloxy-3,5-dimethoxy-phenyl)-5-(3,4,5-trimethoxy-phenyl)-cyclopentanol

Chemical Property:

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Technology Process of (1R,2S,5R)-2-(4-Benzyloxy-3,5-dimethoxy-phenyl)-5-(3,4,5-trimethoxy-phenyl)-cyclopentanol

There total 1 articles about (1R,2S,5R)-2-(4-Benzyloxy-3,5-dimethoxy-phenyl)-5-(3,4,5-trimethoxy-phenyl)-cyclopentanol which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

: 125106-82-3
C₂₉H₃₂O₆

: 143814-95-3
(1R,2S,5R)-2-(4-Benzyloxy-3,5-dimethoxy-phenyl)-5-(3,4,5-trimethoxy-phenyl)-cyclopentanol

Guidance literature:: With sodium hydroxide; dihydrogen peroxide; diborane; Yield given. Multistep reaction; 1.) THF, RT, overnight, 2.) RT, 2 h;
DOI:10.1016/0223-5234(92)90156-U

Reference yield: 86.0%

: 143814-95-3
(1R,2S,5R)-2-(4-Benzyloxy-3,5-dimethoxy-phenyl)-5-(3,4,5-trimethoxy-phenyl)-cyclopentanol

: 74-88-4
methyl iodide

: 143814-96-4
1α-methoxy-2β-(3,4,5-trimethoxyphenyl)-5β-(3,5-dimethoxy-4-benzyloxyphenyl)cyclopentane

Guidance literature:: With sodium hydride; In tetrahydrofuran; at 40 ℃; for 4h;
DOI:10.1016/0223-5234(92)90156-U

Reference yield:

: 143814-95-3
(1R,2S,5R)-2-(4-Benzyloxy-3,5-dimethoxy-phenyl)-5-(3,4,5-trimethoxy-phenyl)-cyclopentanol

: 143814-97-5
1α-methoxy-2β-(3,4,5-trimetoxyphenyl)-5β-(3,5-dimehoxy-4-hydroxyphenyl)cyclopentane

Guidance literature:: Multi-step reaction with 2 steps

1: 86 percent / NaH / tetrahydrofuran / 4 h / 40 °C

2: 89 percent / H₂ / 10percent Pd-C / ethanol; ethyl acetate / 12 h / 760 Torr / Ambient temperature

With hydrogen; sodium hydride; palladium on activated charcoal; In tetrahydrofuran; ethanol; ethyl acetate;
DOI:10.1016/0223-5234(92)90156-U