(E)-N’-((1H-indol-4-yl)methylene)-2-(2-(furan-3-yl)-4,6-dimethylphenoxy)acetohydrazide

Base Information

Chemical Name:(E)-N’-((1H-indol-4-yl)methylene)-2-(2-(furan-3-yl)-4,6-dimethylphenoxy)acetohydrazide
CAS No.:1572184-54-3
Molecular Formula:C₂₃H₂₁N₃O₃
Molecular Weight:387.438
Hs Code.:

Synonyms:(E)-N’-((1H-indol-4-yl)methylene)-2-(2-(furan-3-yl)-4,6-dimethylphenoxy)acetohydrazide

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Chemical Property of (E)-N’-((1H-indol-4-yl)methylene)-2-(2-(furan-3-yl)-4,6-dimethylphenoxy)acetohydrazide

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Technology Process of (E)-N’-((1H-indol-4-yl)methylene)-2-(2-(furan-3-yl)-4,6-dimethylphenoxy)acetohydrazide

There total 4 articles about (E)-N’-((1H-indol-4-yl)methylene)-2-(2-(furan-3-yl)-4,6-dimethylphenoxy)acetohydrazide which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 31.0%

: 1074-86-8
4-formyl indole

: 1572184-89-4
2-(2-(furan-3-yl)-4,6-dimethylphenoxy)acetohydrazide

: 1572184-54-3
(E)-N’-((1H-indol-4-yl)methylene)-2-(2-(furan-3-yl)-4,6-dimethylphenoxy)acetohydrazide

Guidance literature:: In ethanol; at 90 ℃; for 6h;

Reference yield:

: 1572185-39-7
2-(furan-3-yl)-4,6-dimethylphenol

: 1572184-54-3
(E)-N’-((1H-indol-4-yl)methylene)-2-(2-(furan-3-yl)-4,6-dimethylphenoxy)acetohydrazide

Guidance literature:: Multi-step reaction with 3 steps

1: caesium carbonate / acetonitrile / 16 h

2: ethanol / 16 h / Reflux

3: ethanol / 6 h / 90 °C

With caesium carbonate; In ethanol; acetonitrile;

Reference yield:

: 15191-36-3
2-bromo-4,6-dimethylphenol

: 1572184-54-3
(E)-N’-((1H-indol-4-yl)methylene)-2-(2-(furan-3-yl)-4,6-dimethylphenoxy)acetohydrazide

Guidance literature:: Multi-step reaction with 4 steps

1: sodium carbonate; (1,1'-bis(diphenylphosphino)ferrocene)palladium(II) dichloride / tetrahydrofuran / 1 h / Reflux

2: caesium carbonate / acetonitrile / 16 h

3: ethanol / 16 h / Reflux

4: ethanol / 6 h / 90 °C

With (1,1'-bis(diphenylphosphino)ferrocene)palladium(II) dichloride; sodium carbonate; caesium carbonate; In tetrahydrofuran; ethanol; acetonitrile;