tert-butyl 2-oxo-3-phthalimido-2,3,4,5-tetrahydro-1H-1-benzazepine-1-acetate

Base Information

Chemical Name:tert-butyl 2-oxo-3-phthalimido-2,3,4,5-tetrahydro-1H-1-benzazepine-1-acetate
CAS No.:105260-11-5
Molecular Formula:C₂₄H₂₄N₂O₅
Molecular Weight:420.465
Hs Code.:
DSSTox Substance ID:DTXSID301107575

Synonyms:SCHEMBL8895762;OCXJXLFFWOBHNR-UHFFFAOYSA-N;DTXSID301107575;tert-butyl 2-oxo-3-phthalimido-2,3,4,5-tetrahydro-1H-1-benzazepine-1-acetate;105260-11-5;1,1-Dimethylethyl 3-(1,3-dihydro-1,3-dioxo-2H-isoindol-2-yl)-2,3,4,5-tetrahydro-2-oxo-1H-1-benzazepine-1-acetate

Suppliers and Price of tert-butyl 2-oxo-3-phthalimido-2,3,4,5-tetrahydro-1H-1-benzazepine-1-acetate

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

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Chemical Property of tert-butyl 2-oxo-3-phthalimido-2,3,4,5-tetrahydro-1H-1-benzazepine-1-acetate

Chemical Property:

XLogP3:3.3
Hydrogen Bond Donor Count:0
Hydrogen Bond Acceptor Count:5
Rotatable Bond Count:5
Exact Mass:420.16852187
Heavy Atom Count:31
Complexity:734

Purity/Quality:

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:: SDS file from LookChem

Useful:

Canonical SMILES:CC(C)(C)OC(=O)CN1C2=CC=CC=C2CCC(C1=O)N3C(=O)C4=CC=CC=C4C3=O

Technology Process of tert-butyl 2-oxo-3-phthalimido-2,3,4,5-tetrahydro-1H-1-benzazepine-1-acetate

There total 1 articles about tert-butyl 2-oxo-3-phthalimido-2,3,4,5-tetrahydro-1H-1-benzazepine-1-acetate which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

: 86499-96-9
3-bromo-1,3,4,5-tetrahydro-2H-1-benzazepin-2-one

: 105260-11-5
2,3,4,5-tetrahydro-2-oxo-3-phthalimido-1H-1-benzazepin-1-essigsaeure-(tert-butyl)ester

Guidance literature:: Multi-step reaction with 2 steps

1: 83 percent / dimethylformamide / 16 h / 60 °C

2: 93 percent / kalium-(tert-butylat) / dimethylformamide / 1 h / 0 - 5 °C

With potassium tert-butylate; In N,N-dimethyl-formamide;
DOI:10.1002/hlca.19880710205

Reference yield:

: 105260-11-5
2,3,4,5-tetrahydro-2-oxo-3-phthalimido-1H-1-benzazepin-1-essigsaeure-(tert-butyl)ester

: 182561-27-9
(S)-1-t-butyloxycarbonylmethyl-3-amino-2,3,4,5-tetrahydro-1H-[1]benzazepin-2-one tartrate salt

Guidance literature:: Multi-step reaction with 2 steps

1: 85 percent / 2-aminoethanol / 0.08 h / 80 °C

2: 79 percent / C₆H₅CHO / ethanol / 14 h / Heating

With benzaldehyde; ethanolamine; In ethanol;
DOI:10.1002/hlca.19880710205