Hydroxyzine hydrochloride

Base Information

Chemical Name:Hydroxyzine hydrochloride
CAS No.:163837-37-4
Molecular Formula:C₂₁H₂₇ClN₂O₂*2ClH
Molecular Weight:447.832
Hs Code.:
European Community (EC) Number:218-586-3
UNII:76755771U3,5AQ4KXB9U4,GF8H55RPZ9
DSSTox Substance ID:DTXSID2040737
Wikidata:Q27106898
NCI Thesaurus Code:C47559
RXCUI:154987
ChEMBL ID:CHEMBL3186993

Synonyms:2-(2-(4-((4-Chlorophenyl)phenylmethyl)-1-piperazinyl)ethoxy)ethanol;Atarax;Durrax;Hydroxyzine;Hydroxyzine Dihydrochloride;Hydroxyzine Hydrochloride;Hydroxyzine Pamoate;Orgatrax;Pamoate, Hydroxyzine;Vistaril

Suppliers and Price of Hydroxyzine hydrochloride

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
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price

Total 0 raw suppliers

Chemical Property of Hydroxyzine hydrochloride

Chemical Property:

Hydrogen Bond Donor Count:3
Hydrogen Bond Acceptor Count:4
Rotatable Bond Count:8
Exact Mass:446.129461
Heavy Atom Count:28
Complexity:376

Purity/Quality:

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:

Useful:

Canonical SMILES:C1CN(CCN1CCOCCO)C(C2=CC=CC=C2)C3=CC=C(C=C3)Cl.Cl.Cl
Recent ClinicalTrials:Preoperative Use of Alprazolam and Hydroxyzine in Anxiety

Technology Process of Hydroxyzine hydrochloride

There total 1 articles about Hydroxyzine hydrochloride which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

: 303-26-4
N-(4-chlorobenzhydryl)piperazine

: 628-89-7
2-(2-Chloroethoxy)ethanol

: 2192-20-3,163837-37-4
hydroxyzine dihydrochloride

Guidance literature:: N-(4-chlorobenzhydryl)piperazine; With tetrabutylammomium bromide; potassium carbonate; In water; at 25 ℃;

2-(2-Chloroethoxy)ethanol; In water; at 80 ℃; for 5h;

With hydrogenchloride;