(R)-4-benzyl-3-(4-methylpentanoyl)oxazolidin-2-one

Base Information

Chemical Name:(R)-4-benzyl-3-(4-methylpentanoyl)oxazolidin-2-one
CAS No.:163810-26-2
Molecular Formula:C16H21NO3
Molecular Weight:275.348
Hs Code.:2934999090
DSSTox Substance ID:DTXSID90374808
Nikkaji Number:J654.295F
Wikidata:Q82163371
Mol file:163810-26-2.mol

Synonyms:163810-26-2;(R)-4-benzyl-3-(4-methylpentanoyl)oxazolidin-2-one;3-(3'-Isopropyl-1-oxopropyl)-4(R)-(1-phenylmethyl)-2-oxazolidinone;(4R)-4-benzyl-3-(4-methylpentanoyl)-1,3-oxazolidin-2-one;(R)-4-BENZYL-3-(4-METHYL-PENTANOYL)-OXAZOLIDIN-2-ONE;2-Oxazolidinone, 3-(4-methyl-1-oxopentyl)-4-(phenylmethyl)-, (4R)-;DTXSID90374808;3-(3-isopropyl-1-oxopropyl)-4(r)-(1-phenylmethyl)-2-oxazolidinone;MFCD03419264;AKOS015909276;AC-6499;A3640;CS-0171948;3-(4-Methylpentanoyl)-4alpha-benzyl-2-oxazolidinone;3-(3-iso-Propyl-1-oxopropyl)-4(R)-(1-phenylmethyl)-2-oxazolidinone

Suppliers and Price of (R)-4-benzyl-3-(4-methylpentanoyl)oxazolidin-2-one

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

Crysdot
(R)-4-Benzyl-3-(4-methylpentanoyl)oxazolidin-2-one 95+%
5g
$ 431.00

American Custom Chemicals Corporation
(R)-4-BENZYL-3-(4-METHYL-PENTANOYL)-OXAZOLIDIN-2-ONE 95.00%
1G
$ 301.35

American Custom Chemicals Corporation
(R)-4-BENZYL-3-(4-METHYL-PENTANOYL)-OXAZOLIDIN-2-ONE 95.00%
5G
$ 1343.73

AK Scientific
(R)-4-Benzyl-3-(4-methylpentanoyl)oxazolidin-2-one
5g
$ 693.00

Total 11 raw suppliers

Chemical Property of (R)-4-benzyl-3-(4-methylpentanoyl)oxazolidin-2-one

Chemical Property:

Vapor Pressure:2E-07mmHg at 25°C
Refractive Index:1.537
Boiling Point:424.9 °C at 760 mmHg
Flash Point:210.7 °C
PSA：46.61000
Density:1.131g/cm³
LogP:2.95060
Storage Temp.:2-8°C
XLogP3:3.3
Hydrogen Bond Donor Count:0
Hydrogen Bond Acceptor Count:3
Rotatable Bond Count:5
Exact Mass:275.15214353
Heavy Atom Count:20
Complexity:348

Purity/Quality:

97% ^*data from raw suppliers

(R)-4-Benzyl-3-(4-methylpentanoyl)oxazolidin-2-one 95+% ^*data from reagent suppliers

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:: SDS file from LookChem

Useful:

Canonical SMILES:CC(C)CCC(=O)N1C(COC1=O)CC2=CC=CC=C2
Isomeric SMILES:CC(C)CCC(=O)N1[C@@H](COC1=O)CC2=CC=CC=C2

Technology Process of (R)-4-benzyl-3-(4-methylpentanoyl)oxazolidin-2-one

There total 3 articles about (R)-4-benzyl-3-(4-methylpentanoyl)oxazolidin-2-one which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 100.0%

: 646-07-1
4-Methylpentanoic acid

: 40217-17-2,90719-32-7,120574-96-1,102029-44-7
(R)-4-(phenylmethyl)-2-oxazolidinone

: 163810-26-2
(4R)-4-benzyl-3-(4-methylpentanoyl)oxazolidin-2-one

Guidance literature:: 4-Methylpentanoic acid; With pivaloyl chloride; triethylamine; In tetrahydrofuran; at 0 ℃; for 1h;

(R)-4-(phenylmethyl)-2-oxazolidinone; With lithium chloride; In tetrahydrofuran; at 20 ℃; for 38h;
DOI:10.1039/c3ob41338a

Reference yield: 96.0%

: 38136-29-7
4-methylvaleroyl chloride

: 40217-17-2,90719-32-7,120574-96-1,102029-44-7
(R)-4-(phenylmethyl)-2-oxazolidinone

: 163810-26-2
(4R)-4-benzyl-3-(4-methylpentanoyl)oxazolidin-2-one

Guidance literature:: With n-butyllithium; In tetrahydrofuran; hexane; 1.) -78 deg C, 30 min, 2.) -78 deg C, 30 min;
DOI:10.1021/jo00115a028

Reference yield:

: 646-07-1
4-Methylpentanoic acid

: 163810-26-2
(4R)-4-benzyl-3-(4-methylpentanoyl)oxazolidin-2-one

Guidance literature:: Multi-step reaction with 2 steps

1: triethylamine; pivaloyl chloride / tetrahydrofuran / 1 h / -20 °C

2: lithium chloride / tetrahydrofuran / 3 h / -20 - 0 °C

With pivaloyl chloride; triethylamine; lithium chloride; In tetrahydrofuran;
DOI:10.1016/j.tetlet.2012.10.017