(5-((2-(1-methyl-1H-pyrazol-4-yl)phenoxy)methyl)-4,5-dihydroisoxazol-3-yl)methanamine hydrochloride

Base Information

• Chemical Name: (5-((2-(1-methyl-1H-pyrazol-4-yl)phenoxy)methyl)-4,5-dihydroisoxazol-3-yl)methanamine hydrochloride
• CAS No.: 1620293-11-9
• Molecular Formula: C₁₅H₁₈N₄O₂*ClH
• Molecular Weight: 322.794

Synonyms:(5-((2-(1-methyl-1H-pyrazol-4-yl)phenoxy)methyl)-4,5-dihydroisoxazol-3-yl)methanamine hydrochloride

Chemical Property of (5-((2-(1-methyl-1H-pyrazol-4-yl)phenoxy)methyl)-4,5-dihydroisoxazol-3-yl)methanamine hydrochloride

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Technology Process of (5-((2-(1-methyl-1H-pyrazol-4-yl)phenoxy)methyl)-4,5-dihydroisoxazol-3-yl)methanamine hydrochloride

There total 1 articles about (5-((2-(1-methyl-1H-pyrazol-4-yl)phenoxy)methyl)-4,5-dihydroisoxazol-3-yl)methanamine hydrochloride which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 99.0%

→ (5-((2-(1-methyl-1H-pyrazol-4-yl)phenoxy)methyl)-4,5-dihydroisoxazol-3-yl)methanamine hydrochloride (1620293-11-9)

Guidance literature:

With hydrogenchloride; In 1,4-dioxane; at 0 - 20 ℃; for 12h;

Reference yield: 26.1%

phenyl N-(pyridazin-4-yl)carbamate (115136-48-6) + (5-((2-(1-methyl-1H-pyrazol-4-yl)phenoxy)methyl)-4,5-dihydroisoxazol-3-yl)methanamine hydrochloride (1620293-11-9) → 1-((5-((2-(1-methyl-1H-pyrazol-4-yl)phenoxy)methyl)-4,5-dihydroisoxazol-3-yl)methyl)-3-(pyridazin-4-yl)urea (1620291-06-6)

Guidance literature:

With triethylamine; In dimethyl sulfoxide; at 20 ℃; for 16h; Inert atmosphere;

Reference yield: 21.0%

methyl N'-cyano-N-(2-methylpyridin-4-yl)carbamimidothioate + (5-((2-(1-methyl-1H-pyrazol-4-yl)phenoxy)methyl)-4,5-dihydroisoxazol-3-yl)methanamine hydrochloride (1620293-11-9) → 2-cyano-1-((5-((2-(1-methyl-1H-pyrazol-4-yl)phenoxy)methyl)-4,5-dihydroisoxazol-3-yl)methyl)-3-(2-methylpyridin-4-yl)guanidine (1620291-24-8)

Guidance literature:

With pyridine; dmap; triethylamine; at 80 ℃; for 16h;

Downstream raw materials:

phenyl ((5-((2-(1-methyl-1H-pyrazol-4-yl)phenoxy)methyl)-4,5-dihydroisoxazol-3-yl)methyl)carbamate

1-(imidazo[1,2-a]pyridin-6-ylmethyl)-3-((5-((2-(1-methyl-1H-pyrazol-4-yl)phenoxy)methyl)-4,5-dihydroisoxazol-3-yl)methyl)urea

1-((5-((2-(1-methyl-1H-pyrazol-4-yl)phenoxy)methyl)-4,5-dihydroisoxazol-3-yl)methyl)-3-(pyridazin-4-yl)urea

N-((5-((2-(1-methyl-1H-pyrazol-4-yl)phenoxy)methyl)-4,5-dihydroisoxazol-3-yl)methyl)-3,4-dihydropyrrolo[1,2-a]pyrazine-2(1H)-carboxamide

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