Pent-4-enoic acid ((2R,3R,4S,5R,6S)-4,5-dimethoxy-3-pent-4-enyloxy-6-phenylsulfanyl-tetrahydro-pyran-2-ylmethyl)-amide

Base Information

Chemical Name:Pent-4-enoic acid ((2R,3R,4S,5R,6S)-4,5-dimethoxy-3-pent-4-enyloxy-6-phenylsulfanyl-tetrahydro-pyran-2-ylmethyl)-amide
CAS No.:870537-93-2
Molecular Formula:C₂₄H₃₅NO₅S
Molecular Weight:449.612
Hs Code.:

Synonyms:Pent-4-enoic acid ((2R,3R,4S,5R,6S)-4,5-dimethoxy-3-pent-4-enyloxy-6-phenylsulfanyl-tetrahydro-pyran-2-ylmethyl)-amide

Suppliers and Price of Pent-4-enoic acid ((2R,3R,4S,5R,6S)-4,5-dimethoxy-3-pent-4-enyloxy-6-phenylsulfanyl-tetrahydro-pyran-2-ylmethyl)-amide

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

Total 0 raw suppliers

Chemical Property of Pent-4-enoic acid ((2R,3R,4S,5R,6S)-4,5-dimethoxy-3-pent-4-enyloxy-6-phenylsulfanyl-tetrahydro-pyran-2-ylmethyl)-amide

Chemical Property:

Purity/Quality:

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:

Useful:

Technology Process of Pent-4-enoic acid ((2R,3R,4S,5R,6S)-4,5-dimethoxy-3-pent-4-enyloxy-6-phenylsulfanyl-tetrahydro-pyran-2-ylmethyl)-amide

There total 7 articles about Pent-4-enoic acid ((2R,3R,4S,5R,6S)-4,5-dimethoxy-3-pent-4-enyloxy-6-phenylsulfanyl-tetrahydro-pyran-2-ylmethyl)-amide which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 93.0%

: 511274-69-4
C-((2R,3R,4S,5R,6S)-4,5-Dimethoxy-3-pent-4-enyloxy-6-phenylsulfanyl-tetrahydro-pyran-2-yl)-methylamine

: 39716-58-0
pent-4-enoyl chloride

: 870537-93-2
Pent-4-enoic acid ((2R,3R,4S,5R,6S)-4,5-dimethoxy-3-pent-4-enyloxy-6-phenylsulfanyl-tetrahydro-pyran-2-ylmethyl)-amide

Guidance literature:: With pyridine; dmap; In dichloromethane; at 0 - 20 ℃; for 2.33333h;
DOI:10.1021/jo051021k

Reference yield:

: 511274-40-1
(2R,3R,4S,5R,6S)-2-Hydroxymethyl-4,5-dimethoxy-6-phenylsulfanyl-tetrahydro-pyran-3-ol

: 870537-93-2
Pent-4-enoic acid ((2R,3R,4S,5R,6S)-4,5-dimethoxy-3-pent-4-enyloxy-6-phenylsulfanyl-tetrahydro-pyran-2-ylmethyl)-amide

Guidance literature:: Multi-step reaction with 5 steps

1: 90 percent / triethylamine / CH₂Cl₂ / 24 h / 20 °C

2: 84 percent / NaN₃; 15-crown-5 / dimethylformamide / 48 h / 60 °C

3: 52 percent / tetrabutylammonium iodide; NaH / tetrahydrofuran; various solvent(s) / 24 h / 20 °C

4: 93 percent / PPh₃; H₂O / tetrahydrofuran / 48 h / 20 °C

5: 93 percent / pyridine; DMAP / CH₂Cl₂ / 2.33 h / 0 - 20 °C

With pyridine; dmap; sodium azide; 15-crown-5; water; tetra-(n-butyl)ammonium iodide; sodium hydride; triethylamine; triphenylphosphine; In tetrahydrofuran; dichloromethane; N,N-dimethyl-formamide;
DOI:10.1021/jo051021k

Reference yield:

: 511274-64-9
(2R,3R,4S,5R,6S)-2-Azidomethyl-4,5-dimethoxy-6-phenylsulfanyl-tetrahydro-pyran-3-ol

: 870537-93-2
Pent-4-enoic acid ((2R,3R,4S,5R,6S)-4,5-dimethoxy-3-pent-4-enyloxy-6-phenylsulfanyl-tetrahydro-pyran-2-ylmethyl)-amide

Guidance literature:: Multi-step reaction with 3 steps

1: 52 percent / tetrabutylammonium iodide; NaH / tetrahydrofuran; various solvent(s) / 24 h / 20 °C

2: 93 percent / PPh₃; H₂O / tetrahydrofuran / 48 h / 20 °C

3: 93 percent / pyridine; DMAP / CH₂Cl₂ / 2.33 h / 0 - 20 °C

With pyridine; dmap; water; tetra-(n-butyl)ammonium iodide; sodium hydride; triphenylphosphine; In tetrahydrofuran; dichloromethane;
DOI:10.1021/jo051021k