C₇₉H₁₂₅BrSi₄O₁₄CH₂

Base Information

Chemical Name:C₇₉H₁₂₅BrSi₄O₁₄CH₂
CAS No.:262614-94-8
Molecular Formula:C₈₀H₁₂₇BrO₁₄Si₄
Molecular Weight:1505.13
Hs Code.:

C<sub>79</sub>H<sub>125</sub>BrSi<sub>4</sub>O<sub>14</sub>CH<sub>2</sub>

Synonyms:C₇₉H₁₂₅BrSi₄O₁₄CH₂

Suppliers and Price of C₇₉H₁₂₅BrSi₄O₁₄CH₂

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

Total 0 raw suppliers

Chemical Property of C₇₉H₁₂₅BrSi₄O₁₄CH₂

Chemical Property:

Purity/Quality:

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:

Useful:

Technology Process of C₇₉H₁₂₅BrSi₄O₁₄CH₂

There total 21 articles about C₇₉H₁₂₅BrSi₄O₁₄CH₂ which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 67.0%

: 262614-92-6
(2R,3S)-4-[(2S,4S,6R,8R,10S)-8-Benzyloxymethyl-10-(tert-butyl-diphenyl-silanyloxy)-4-methoxy-1,7-dioxa-spiro[5.5]undec-2-yl]-3-(tert-butyl-dimethyl-silanyloxy)-2-methyl-butyraldehyde

: 262614-93-7
(2R,4S,6R,8S,10S)-8-[2-(2-Bromo-benzyloxy)-ethyl]-4-(tert-butyl-dimethyl-silanyloxy)-4-methyl-10-(2-trimethylsilanyl-ethoxymethoxy)-2-((Z)-2-trimethylsilanyloxy-but-2-enyl)-1,7-dioxa-spiro[5.5]undecane

: 262614-94-8
C₇₉H₁₂₅BrSi₄O₁₄CH₂

Guidance literature:: With boron trifluoride diethyl etherate; In toluene; at -78 ℃; for 1.5h;
DOI:10.1021/ol0000049

Reference yield:

: 69739-34-0
t-butyldimethylsiyl triflate

: 262614-94-8
C₇₉H₁₂₅BrSi₄O₁₄CH₂

Guidance literature:: Multi-step reaction with 9 steps

1.1: 93 percent / DIPEA / CH₂Cl₂ / -40 - 0 °C

2.1: 90 percent / DDQ; H₂O / CH₂Cl₂ / 1 h / 20 °C

3.1: 82 percent / I₂; PPh₃; imidazole / benzene / 1.5 h / 20 °C

4.1: 100 percent / dimethylformamide / 36 h / 65 °C

5.1: (i-Pr₂)AlH / CH₂Cl₂ / 0.33 h / -78 °C

6.1: diethyl ether / 3 h / -78 - 9 °C

7.1: 99 percent / TPAP; NMP; 4 Angstroem MS / CH₂Cl₂ / 9 h / 20 °C

8.1: LiN(PhMe₂Si)2 / tetrahydrofuran / 1 h / -78 °C

8.2: 35 percent / tetrahydrofuran / 6 h / -78 - 20 °C

9.1: 67 percent / BF₃*Et₂O / toluene / 1.5 h / -78 °C

With 1H-imidazole; 1-methyl-pyrrolidin-2-one; tetrapropylammonium perruthennate; lithium bis(dimethylphenylsilyl)amide; 4 Angstroem MS; boron trifluoride diethyl etherate; water; iodine; diisopropyl aluminium hydride; N-ethyl-N,N-diisopropylamine; triphenylphosphine; 2,3-dicyano-5,6-dichloro-p-benzoquinone; In tetrahydrofuran; diethyl ether; dichloromethane; N,N-dimethyl-formamide; toluene; benzene; 1.1: Condensation / 2.1: Hydrolysis / 3.1: Substitution / 4.1: Substitution / 5.1: Reduction / 6.1: Grignard reaction / 7.1: Oxidation / 8.1: Metallation / 8.2: Substitution / 9.1: Mukaiyama aldol reaction;
DOI:10.1021/ol0000049

Reference yield:

: 76513-69-4
(2-trimethylethylsilylethoxy)methyl chloride

: 262614-94-8
C₇₉H₁₂₅BrSi₄O₁₄CH₂

Guidance literature:: Multi-step reaction with 13 steps

1.1: 95 percent / DIPEA; Bu₄NI / tetrahydrofuran / 24 h / 20 °C

2.1: 98 percent / Dibal-H / CH₂Cl₂ / 0.75 h / -78 °C

3.1: 96 percent / TPAP; NMO; 4 Angstroem MS / CH₂Cl₂ / 1 h / 20 °C

4.1: 93 percent / tetrahydrofuran; diethyl ether / 2.5 h / -78 - 0 °C

5.1: 93 percent / DIPEA / CH₂Cl₂ / -40 - 0 °C

6.1: 90 percent / DDQ; H₂O / CH₂Cl₂ / 1 h / 20 °C

7.1: 82 percent / I₂; PPh₃; imidazole / benzene / 1.5 h / 20 °C

8.1: 100 percent / dimethylformamide / 36 h / 65 °C

9.1: (i-Pr₂)AlH / CH₂Cl₂ / 0.33 h / -78 °C

10.1: diethyl ether / 3 h / -78 - 9 °C

11.1: 99 percent / TPAP; NMP; 4 Angstroem MS / CH₂Cl₂ / 9 h / 20 °C

12.1: LiN(PhMe₂Si)2 / tetrahydrofuran / 1 h / -78 °C

12.2: 35 percent / tetrahydrofuran / 6 h / -78 - 20 °C

13.1: 67 percent / BF₃*Et₂O / toluene / 1.5 h / -78 °C

With 1H-imidazole; 1-methyl-pyrrolidin-2-one; N-methyl-2-indolinone; tetrapropylammonium perruthennate; lithium bis(dimethylphenylsilyl)amide; 4 Angstroem MS; boron trifluoride diethyl etherate; water; iodine; tetra-(n-butyl)ammonium iodide; diisobutylaluminium hydride; diisopropyl aluminium hydride; N-ethyl-N,N-diisopropylamine; triphenylphosphine; 2,3-dicyano-5,6-dichloro-p-benzoquinone; In tetrahydrofuran; diethyl ether; dichloromethane; N,N-dimethyl-formamide; toluene; benzene; 1.1: Condensation / 2.1: Reduction / 3.1: Oxidation / 4.1: Addition / 5.1: Condensation / 6.1: Hydrolysis / 7.1: Substitution / 8.1: Substitution / 9.1: Reduction / 10.1: Grignard reaction / 11.1: Oxidation / 12.1: Metallation / 12.2: Substitution / 13.1: Mukaiyama aldol reaction;
DOI:10.1021/ol0000049