N--glycin-ethylester

Base Information

• Chemical Name: N--glycin-ethylester
• CAS No.: 4526-91-4
• Molecular Formula: C₁₅H₂₀N₂O₅S
• Molecular Weight: 340.4
• Mol file: 4526-91-4.mol

Synonyms:N--glycin-ethylester

Chemical Property of N--glycin-ethylester

Chemical Property:

Purity/Quality:

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

Useful:

Technology Process of N--glycin-ethylester

There total 5 articles about N--glycin-ethylester which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

ethyl S-triphenylmethyl-N-benzoxycarbonyl-L-cysteinyl-glycinate (3695-78-1) → N--glycin-ethylester (4526-91-4)

Guidance literature:

With pyridine; silver nitrate; In methanol;

DOI:10.1021/ja00879a019

Reference yield:

N-benzyloxycarbonyl-S-trityl-L-cysteine (26311-04-6) → N--glycin-ethylester (4526-91-4)

Guidance literature:

Multi-step reaction with 2 steps

1: DCC, Et₃N / CHCl₃

2: Py, AgNO₃ / methanol

With pyridine; silver nitrate; triethylamine; dicyclohexyl-carbodiimide; In methanol; chloroform;

DOI:10.1021/ja00879a019

Reference yield:

((R)-2-Benzyloxycarbonylamino-3-ethylcarbamoylsulfanyl-propionylamino)-acetic acid ethyl ester (10285-42-4) → N--glycin-ethylester (4526-91-4)

Guidance literature:

Multistep reaction; (i) Hg(OAc)2, aq. AcOH, (ii) H₂S;

DOI:10.1021/ja00772a040

upstream raw materials:

ethyl S-triphenylmethyl-N-benzoxycarbonyl-L-cysteinyl-glycinate

((R)-2-Benzyloxycarbonylamino-3-ethylcarbamoylsulfanyl-propionylamino)-acetic acid ethyl ester

N-benzyloxycarbonyl-L-cysteine

GlyOEt*HCl