methyl 4-trifluoromethylphenyldiazoacetate

Base Information

Chemical Name:methyl 4-trifluoromethylphenyldiazoacetate
CAS No.:219564-85-9
Molecular Formula:C₁₀H₇F₃N₂O₂
Molecular Weight:244.173
Hs Code.:

Synonyms:methyl 4-trifluoromethylphenyldiazoacetate

Suppliers and Price of methyl 4-trifluoromethylphenyldiazoacetate

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

Total 0 raw suppliers

Chemical Property of methyl 4-trifluoromethylphenyldiazoacetate

Chemical Property:

Purity/Quality:

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:

Useful:

Technology Process of methyl 4-trifluoromethylphenyldiazoacetate

There total 4 articles about methyl 4-trifluoromethylphenyldiazoacetate which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 96.0%

: 135325-18-7
methyl 2-(4-(trifluoromethyl)phenyl)acetate

: 219564-85-9
methyl 4-trifluoromethylphenyldiazoacetate

Guidance literature:: With 4-acetamidobenzenesulfonyl azide; 1,8-diazabicyclo[5.4.0]undec-7-ene; In acetonitrile; at 0 - 20 ℃; Inert atmosphere;
DOI:10.1002/adsc.201901343

Reference yield:

: 32857-62-8
4-Trifluoromethylphenylacetic acid

: 219564-85-9
methyl 4-trifluoromethylphenyldiazoacetate

Guidance literature:: Multi-step reaction with 2 steps

1: thionyl chloride / 16 h / 0 - 20 °C / Inert atmosphere

2: 4-acetamidobenzenesulfonyl azide; 1,8-diazabicyclo[5.4.0]undec-7-ene / acetone / 20 °C / Inert atmosphere

With thionyl chloride; 4-acetamidobenzenesulfonyl azide; 1,8-diazabicyclo[5.4.0]undec-7-ene; In acetone;
DOI:10.1039/c5ob02259b

Reference yield:

: 941-55-9
4-toluenesulfonyl azide

: 135325-18-7
methyl 2-(4-(trifluoromethyl)phenyl)acetate

: 219564-85-9
methyl 4-trifluoromethylphenyldiazoacetate

Guidance literature:: With 1,8-diazabicyclo[5.4.0]undec-7-ene; In acetonitrile; at 0 - 22 ℃; for 24h; Inert atmosphere;
DOI:10.1021/acs.orglett.9b02692