4-Ethoxycarbonylmethyl-1,2,3,4-tetrahydro-naphthalene-2-carboxylic acid methyl ester

Base Information

Chemical Name:4-Ethoxycarbonylmethyl-1,2,3,4-tetrahydro-naphthalene-2-carboxylic acid methyl ester
CAS No.:118588-48-0
Molecular Formula:C₁₆H₂₀O₄
Molecular Weight:276.332
Hs Code.:

Synonyms:4-Ethoxycarbonylmethyl-1,2,3,4-tetrahydro-naphthalene-2-carboxylic acid methyl ester

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Chemical Property of 4-Ethoxycarbonylmethyl-1,2,3,4-tetrahydro-naphthalene-2-carboxylic acid methyl ester

Chemical Property:

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Technology Process of 4-Ethoxycarbonylmethyl-1,2,3,4-tetrahydro-naphthalene-2-carboxylic acid methyl ester

There total 2 articles about 4-Ethoxycarbonylmethyl-1,2,3,4-tetrahydro-naphthalene-2-carboxylic acid methyl ester which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 20.0%

: 83781-55-9
benzyl>trimethylammonium iodide

: 24393-48-4
ethyl trans-2-methylcinnamate

: 118588-48-0
4-Ethoxycarbonylmethyl-1,2,3,4-tetrahydro-naphthalene-2-carboxylic acid methyl ester

: 344318-59-8
1-(carbethoxymethyl)-2-carbomethoxy-1,2,3,4-tetrahydronaphthalene

Guidance literature:: With tetra(tert-butyl)-ammonium fluoride; acrylic acid methyl ester; In acetonitrile; for 1h; Yields of byproduct given; Ambient temperature;
DOI:10.1021/ja00390a036

Reference yield:

: 83781-55-9
benzyl>trimethylammonium iodide

: 292638-85-8,9003-21-8,96-33-3
acrylic acid methyl ester

: 24393-48-4
ethyl trans-2-methylcinnamate

: 118588-48-0
4-Ethoxycarbonylmethyl-1,2,3,4-tetrahydro-naphthalene-2-carboxylic acid methyl ester

: 344318-59-8
1-(carbethoxymethyl)-2-carbomethoxy-1,2,3,4-tetrahydronaphthalene

Guidance literature:: With tetra(tert-butyl)-ammonium fluoride; In acetonitrile; for 1h; Yield given. Yields of byproduct given. Title compound not separated from byproducts; Ambient temperature;
DOI:10.1021/ja00390a036