[3-(1,3-Dioxan-2-yl)phenyl]methanol

Base Information

Chemical Name:[3-(1,3-Dioxan-2-yl)phenyl]methanol
CAS No.:163164-08-7
Molecular Formula:C11H14 O3
Molecular Weight:194.23
Hs Code.:
DSSTox Substance ID:DTXSID60438885
Mol file:163164-08-7.mol

Synonyms:[3-(1,3-dioxan-2-yl)phenyl]methanol;163164-08-7;Benzenemethanol, 3-(1,3-dioxan-2-yl)- (9CI);DTXSID60438885

Suppliers and Price of [3-(1,3-Dioxan-2-yl)phenyl]methanol

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

Total 2 raw suppliers

Chemical Property of [3-(1,3-Dioxan-2-yl)phenyl]methanol

Chemical Property:

Boiling Point:346.1±37.0 °C(Predicted)
PKA:14.31±0.10(Predicted)
PSA：38.69000
Density:1.166±0.06 g/cm3(Predicted)
LogP:1.61440
XLogP3:0.8
Hydrogen Bond Donor Count:1
Hydrogen Bond Acceptor Count:3
Rotatable Bond Count:2
Exact Mass:194.094294304
Heavy Atom Count:14
Complexity:166

Purity/Quality:: 99% ^*data from raw suppliers

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:: SDS file from LookChem

Useful:

Canonical SMILES:C1COC(OC1)C2=CC=CC(=C2)CO

Technology Process of [3-(1,3-Dioxan-2-yl)phenyl]methanol

There total 3 articles about [3-(1,3-Dioxan-2-yl)phenyl]methanol which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 93.0%

: 169339-42-8
2-(3-formylphenyl)-1,3-dioxane

: 163164-08-7
2-<3-(hydroxymethyl)phenyl>-1,3-dioxane

Guidance literature:: With lithium aluminium tetrahydride; In diethyl ether; at 0 ℃; for 2h;
DOI:10.1021/jm00010a005

Reference yield:

: 3132-99-8
m-bromobenzoic aldehyde

: 163164-08-7
2-<3-(hydroxymethyl)phenyl>-1,3-dioxane

Guidance literature:: Multi-step reaction with 3 steps

1: 99 percent / p-toluenesulfonic acid / toluene / 2.5 h / Heating

2: 1.) n-BuLi / 1.) hexane, THF, from -100 deg C to -78 deg C, 1 h 25 min, 2.) hexane, THF, -70 deg C, 1 h

3: 93 percent / LiAlH₄ / diethyl ether / 2 h / 0 °C

With lithium aluminium tetrahydride; n-butyllithium; toluene-4-sulfonic acid; In diethyl ether; toluene;
DOI:10.1021/jm00010a005

Reference yield:

: 67437-93-8
2-(3-bromophenyl)-[1,3]dioxane

: 163164-08-7
2-<3-(hydroxymethyl)phenyl>-1,3-dioxane

Guidance literature:: Multi-step reaction with 2 steps

1: 1.) n-BuLi / 1.) hexane, THF, from -100 deg C to -78 deg C, 1 h 25 min, 2.) hexane, THF, -70 deg C, 1 h

2: 93 percent / LiAlH₄ / diethyl ether / 2 h / 0 °C

With lithium aluminium tetrahydride; n-butyllithium; In diethyl ether;
DOI:10.1021/jm00010a005