phenylmethyl [2R-hydroxy-3-[(3-methylbutyl) (methylsulfonyl)amino]-1S-(phenylmethyl)-propyl]carbamate

Base Information

• Chemical Name: phenylmethyl [2R-hydroxy-3-[(3-methylbutyl) (methylsulfonyl)amino]-1S-(phenylmethyl)-propyl]carbamate
• CAS No.: 157445-94-8
• Molecular Formula: C₂₄H₃₄N₂O₅S
• Molecular Weight: 462.61
• Mol file: 157445-94-8.mol

Synonyms:phenylmethyl [2R-hydroxy-3-[(3-methylbutyl) (methylsulfonyl)amino]-1S-(phenylmethyl)-propyl]carbamate

Chemical Property of phenylmethyl [2R-hydroxy-3-[(3-methylbutyl) (methylsulfonyl)amino]-1S-(phenylmethyl)-propyl]carbamate

Chemical Property:

Purity/Quality:

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

Useful:

Technology Process of phenylmethyl [2R-hydroxy-3-[(3-methylbutyl) (methylsulfonyl)amino]-1S-(phenylmethyl)-propyl]carbamate

There total 1 articles about phenylmethyl [2R-hydroxy-3-[(3-methylbutyl) (methylsulfonyl)amino]-1S-(phenylmethyl)-propyl]carbamate which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

methanesulfonyl chloride (124-63-0) + N-[3(S)-benzyloxycarbonylamino-2(R)-hydroxy-4-phenylbutyl]isoamylamine (143225-04-1) → phenylmethyl [2R-hydroxy-3-[(3-methylbutyl) (methylsulfonyl)amino]-1S-(phenylmethyl)-propyl]carbamate (157445-94-8)

Guidance literature:

With triethylamine; In dichloromethane;

DOI:10.1021/jm00004a001

Reference yield:

phenylmethyl [2R-hydroxy-3-[(3-methylbutyl) (methylsulfonyl)amino]-1S-(phenylmethyl)-propyl]carbamate (157445-94-8) → N1-[2R-hydroxy-3-[(3-methylbutyl) (methyl-sulfonyl)amino]1S-(phenylmethyl)propyl]l-2S-[(2-quinolinylcarbonyl)amino]butanediamide

Guidance literature:

palladium; In methanol;

Reference yield:

phenylmethyl [2R-hydroxy-3-[(3-methylbutyl) (methylsulfonyl)amino]-1S-(phenylmethyl)-propyl]carbamate (157445-94-8) → N-((2R,3S)-3-Amino-2-hydroxy-4-phenyl-butyl)-N-(3-methyl-butyl)-methanesulfonamide

Guidance literature:

With hydrogen; palladium on activated charcoal; In methanol;

DOI:10.1021/jm00004a001

upstream raw materials:

methanesulfonyl chloride

N-[3(S)-benzyloxycarbonylamino-2(R)-hydroxy-4-phenylbutyl]isoamylamine