4-Methyl-2-[4'-trifluoromethyl-5-(6-trifluoromethyl-piperidin-2-yl)-biphenyl-3-yl]-pentanoic acid ethyl ester

Base Information

Chemical Name:4-Methyl-2-[4'-trifluoromethyl-5-(6-trifluoromethyl-piperidin-2-yl)-biphenyl-3-yl]-pentanoic acid ethyl ester
CAS No.:1145683-06-2
Molecular Formula:C₂₇H₃₁F₆NO₂
Molecular Weight:515.539
Hs Code.:

Synonyms:4-Methyl-2-[4'-trifluoromethyl-5-(6-trifluoromethyl-piperidin-2-yl)-biphenyl-3-yl]-pentanoic acid ethyl ester

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Chemical Property of 4-Methyl-2-[4'-trifluoromethyl-5-(6-trifluoromethyl-piperidin-2-yl)-biphenyl-3-yl]-pentanoic acid ethyl ester

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Technology Process of 4-Methyl-2-[4'-trifluoromethyl-5-(6-trifluoromethyl-piperidin-2-yl)-biphenyl-3-yl]-pentanoic acid ethyl ester

There total 1 articles about 4-Methyl-2-[4'-trifluoromethyl-5-(6-trifluoromethyl-piperidin-2-yl)-biphenyl-3-yl]-pentanoic acid ethyl ester which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 99.0%

: 1145683-05-1
4-Methyl-2-[4'-trifluoromethyl-5-(6-trifluoromethyl-pyridin-2-yl)-biphenyl-3-yl]-pentanoic acid ethyl ester

: 1145683-06-2
4-Methyl-2-[4'-trifluoromethyl-5-(6-trifluoromethyl-piperidin-2-yl)-biphenyl-3-yl]-pentanoic acid ethyl ester

Guidance literature:: With hydrogenchloride; hydrogen; platinum(IV) oxide; In 1,4-dioxane; ethanol; for 1h; under 1034.32 Torr; Product distribution / selectivity;

Reference yield: 100.0%

: 1145683-06-2
4-Methyl-2-[4'-trifluoromethyl-5-(6-trifluoromethyl-piperidin-2-yl)-biphenyl-3-yl]-pentanoic acid ethyl ester

: 100-39-0
benzyl bromide

: 1145683-09-5
2-[5-(1-Benzyl-6-trifluoromethyl-piperidin-2-yl)-4'-trifluoromethyl-biphenyl-3-yl]-4-methyl-pentanoic acid ethyl ester

Guidance literature:: With tetra-(n-butyl)ammonium iodide; N-ethyl-N,N-diisopropylamine; In acetonitrile; at 150 ℃; for 0.5h; microwave irradiation;

Reference yield: 69.0%

: 1145683-06-2
4-Methyl-2-[4'-trifluoromethyl-5-(6-trifluoromethyl-piperidin-2-yl)-biphenyl-3-yl]-pentanoic acid ethyl ester

: 590-86-3
isovaleraldehyde

: 1145683-15-3
C₃₂H₄₁F₆NO₂

Guidance literature:: 4-Methyl-2-[4'-trifluoromethyl-5-(6-trifluoromethyl-piperidin-2-yl)-biphenyl-3-yl]-pentanoic acid ethyl ester; isovaleraldehyde; In tetrahydrofuran; for 1h;

With sodium tris(acetoxy)borohydride; In tetrahydrofuran; for 48h;

With sodium hydrogencarbonate; In tetrahydrofuran; water; ethyl acetate;