tert-butyl 3-[4-[(5,6,7,8-tetrahydro-5,5,8,8-tetramethyl-2-naphthyl)carbamoyl]phenyl]-3-oxopropionate

Base Information

Chemical Name:tert-butyl 3-[4-[(5,6,7,8-tetrahydro-5,5,8,8-tetramethyl-2-naphthyl)carbamoyl]phenyl]-3-oxopropionate
CAS No.:1489126-48-8
Molecular Formula:C₂₈H₃₅NO₄
Molecular Weight:449.59
Hs Code.:

Synonyms:tert-butyl 3-[4-[(5,6,7,8-tetrahydro-5,5,8,8-tetramethyl-2-naphthyl)carbamoyl]phenyl]-3-oxopropionate

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Chemical Property of tert-butyl 3-[4-[(5,6,7,8-tetrahydro-5,5,8,8-tetramethyl-2-naphthyl)carbamoyl]phenyl]-3-oxopropionate

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Technology Process of tert-butyl 3-[4-[(5,6,7,8-tetrahydro-5,5,8,8-tetramethyl-2-naphthyl)carbamoyl]phenyl]-3-oxopropionate

There total 1 articles about tert-butyl 3-[4-[(5,6,7,8-tetrahydro-5,5,8,8-tetramethyl-2-naphthyl)carbamoyl]phenyl]-3-oxopropionate which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 59.0%

: 540-88-5
acetic acid tert-butyl ester

: 94497-53-7
methyl 4-[(5,6,7,8-tetrahydro-5,5,8,8-tetramethyl-2-naphthyl)-carbamoyl]benzoate

: 1489126-48-8
tert-butyl 3-[4-[(5,6,7,8-tetrahydro-5,5,8,8-tetramethyl-2-naphthyl)carbamoyl]phenyl]-3-oxopropionate

: 1489126-50-2
di-tert-butyl 3-hydroxy-3-[4-[(5,6,7,8-tetrahydro-5,5,8,8-tetramethyl-2-naphthyl)carbamoyl]phenyl]glutarate

Guidance literature:: acetic acid tert-butyl ester; With n-butyllithium; diisopropylamine; In tetrahydrofuran; hexane; at -78 ℃; for 0.5h;

methyl 4-[(5,6,7,8-tetrahydro-5,5,8,8-tetramethyl-2-naphthyl)-carbamoyl]benzoate; In tetrahydrofuran; hexane; at -78 - 20 ℃; for 4h;
DOI:10.1248/cpb.c13-00356