C₆₀H₇₈B₂N₆O₁₁

Base Information

• Chemical Name: C₆₀H₇₈B₂N₆O₁₁
• CAS No.: 914912-86-0
• Molecular Formula: C₆₀H₇₈B₂N₆O₁₁
• Molecular Weight: 1080.93
• Mol file: 914912-86-0.mol

Synonyms:C₆₀H₇₈B₂N₆O₁₁

Chemical Property of C₆₀H₇₈B₂N₆O₁₁

Chemical Property:

Purity/Quality:

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

Useful:

Technology Process of C₆₀H₇₈B₂N₆O₁₁

There total 7 articles about C₆₀H₇₈B₂N₆O₁₁ which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

allyl 3-amino-5-(tert-butoxycarbonylamino)benzoate (914912-82-6) → C60H78B2N6O11 (914912-86-0)

Guidance literature:

Multi-step reaction with 6 steps

1.1: sodium cyanoborohydride; acetic acid / ethanol / 32 h / 20 °C

1.2: 60 percent / toluene / Heating

2.1: 98 percent / sodium cyanoborohydride; acetic acid / ethanol; H₂O / 18 h / 20 °C

3.1: HCl / dioxane / 2 h / 0 - 5 °C

4.1: 4.8 g / chlorotripyrrolidinophosphonium hexafluorophosphate; N-ethyldiisopropylamine / CH₂Cl₂ / 18 h / 20 °C

5.1: HCl / dioxane / 2 h / 0 - 5 °C

6.1: 2.3 g / chlorotripyrrolidinophosphonium hexafluorophosphate; N-ethyldiisopropylamine / CH₂Cl₂

With hydrogenchloride; sodium cyanoborohydride; acetic acid; N-ethyl-N,N-diisopropylamine; chlorotri(pyrrolidin-1-yl)phosphonium hexafluorophosphate; In 1,4-dioxane; ethanol; dichloromethane; water;

DOI:10.1002/ejoc.200600245

Reference yield:

allyl 3-(tert-butoxycarbonylamino)-5-{methyl[2-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)benzyl]amino}benzoate (914912-84-8) → C60H78B2N6O11 (914912-86-0)

Guidance literature:

Multi-step reaction with 4 steps

1: HCl / dioxane / 2 h / 0 - 5 °C

2: 4.8 g / chlorotripyrrolidinophosphonium hexafluorophosphate; N-ethyldiisopropylamine / CH₂Cl₂ / 18 h / 20 °C

3: HCl / dioxane / 2 h / 0 - 5 °C

4: 2.3 g / chlorotripyrrolidinophosphonium hexafluorophosphate; N-ethyldiisopropylamine / CH₂Cl₂

With hydrogenchloride; N-ethyl-N,N-diisopropylamine; chlorotri(pyrrolidin-1-yl)phosphonium hexafluorophosphate; In 1,4-dioxane; dichloromethane;

DOI:10.1002/ejoc.200600245

Reference yield:

3-amino-5-{methyl-[2-(4,4,5,5-tetramethyl-[1,3,2]dioxaborolan-2-yl)-benzyl]-amino}-benzoic acid allyl ester → C60H78B2N6O11 (914912-86-0)

Guidance literature:

Multi-step reaction with 3 steps

1: 4.8 g / chlorotripyrrolidinophosphonium hexafluorophosphate; N-ethyldiisopropylamine / CH₂Cl₂ / 18 h / 20 °C

2: HCl / dioxane / 2 h / 0 - 5 °C

3: 2.3 g / chlorotripyrrolidinophosphonium hexafluorophosphate; N-ethyldiisopropylamine / CH₂Cl₂

With hydrogenchloride; N-ethyl-N,N-diisopropylamine; chlorotri(pyrrolidin-1-yl)phosphonium hexafluorophosphate; In 1,4-dioxane; dichloromethane;

DOI:10.1002/ejoc.200600245

upstream raw materials:

allyl 3-amino-5-(tert-butoxycarbonylamino)benzoate

allyl 3-(tert-butoxycarbonylamino)-5-{methyl[2-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)benzyl]amino}benzoate

allyl 3-(tert-butoxycarbonylamino)-5-[2-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)benzylamino]benzoate

3,5-di-(tert-butyloxycarbonylamino)benzoic acid

Downstream raw materials:

C₅₂H₆₄B₂N₆O₈

C₄₀H₄₄B₂N₆O₈