(S,E)-N₁,N₅-bis(3,5-difluorophenyl)-2-(3-(3,4-dimethoxyphenyl)acrylamido)pentanediamide

Base Information

• Chemical Name: (S,E)-N₁,N₅-bis(3,5-difluorophenyl)-2-(3-(3,4-dimethoxyphenyl)acrylamido)pentanediamide
• CAS No.: 1158726-81-8
• Molecular Formula: C₂₈H₂₅F₄N₃O₅
• Molecular Weight: 559.517

Synonyms:(S,E)-N₁,N₅-bis(3,5-difluorophenyl)-2-(3-(3,4-dimethoxyphenyl)acrylamido)pentanediamide

Chemical Property of (S,E)-N₁,N₅-bis(3,5-difluorophenyl)-2-(3-(3,4-dimethoxyphenyl)acrylamido)pentanediamide

Chemical Property:

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Technology Process of (S,E)-N₁,N₅-bis(3,5-difluorophenyl)-2-(3-(3,4-dimethoxyphenyl)acrylamido)pentanediamide

There total 1 articles about (S,E)-N₁,N₅-bis(3,5-difluorophenyl)-2-(3-(3,4-dimethoxyphenyl)acrylamido)pentanediamide which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 44.6%

(S,E)-2-(3-(3,4-dimethoxyphenyl)acrylamido)pentanedioic acid (1158726-84-1) + 3,5-difluoroaniline (372-39-4) → (S,E)-N1,N5-bis(3,5-difluorophenyl)-2-(3-(3,4-dimethoxyphenyl)acrylamido)pentanediamide (1158726-81-8)

Guidance literature:

With dicyclohexyl-carbodiimide; In chloroform; at -5 ℃; Inert atmosphere;

DOI:10.1016/j.bmc.2009.03.017

upstream raw materials:

(S,E)-2-(3-(3,4-dimethoxyphenyl)acrylamido)pentanedioic acid

3,5-difluoroaniline

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