4,5-Diphenyl-2-[12-(tetrahydro-pyran-2-yloxy)-dodecyl]-oxazole

Base Information

• Chemical Name: 4,5-Diphenyl-2-[12-(tetrahydro-pyran-2-yloxy)-dodecyl]-oxazole
• CAS No.: 411237-97-3
• Molecular Formula: C₃₂H₄₃NO₃
• Molecular Weight: 489.698
• Mol file: 411237-97-3.mol

Synonyms:4,5-Diphenyl-2-[12-(tetrahydro-pyran-2-yloxy)-dodecyl]-oxazole

Chemical Property of 4,5-Diphenyl-2-[12-(tetrahydro-pyran-2-yloxy)-dodecyl]-oxazole

Chemical Property:

Purity/Quality:

Safty Information:

• Pictogram(s):  
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MSDS Files:

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Technology Process of 4,5-Diphenyl-2-[12-(tetrahydro-pyran-2-yloxy)-dodecyl]-oxazole

There total 1 articles about 4,5-Diphenyl-2-[12-(tetrahydro-pyran-2-yloxy)-dodecyl]-oxazole which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

2-methyl-4,5-diphenyloxazole (14224-99-8) + 2-[(11-iodoundecyl)oxy]tetrahydro-2H-pyran (81819-10-5) → 4,5-Diphenyl-2-[12-(tetrahydro-pyran-2-yloxy)-dodecyl]-oxazole (411237-97-3)

Guidance literature:

With lithium diisopropyl amide; Yield given. Multistep reaction; 1.) THF, -78 deg C, 1.5h, 2.) -78 deg C, 10 min;

DOI:10.1016/S0040-4039(01)90426-5

Reference yield:

4,5-Diphenyl-2-[12-(tetrahydro-pyran-2-yloxy)-dodecyl]-oxazole (411237-97-3) → N-benzoylbenzamide (614-28-8)

Guidance literature:

Multi-step reaction with 3 steps

1: 2N HCl / tetrahydrofuran / 3 h / 60 °C

2: oxygen, Sensitox (Rose Bengal polymer) / CH₂Cl₂ / 0.5 h / Irradiation

3: p-toluenesulfonic acid / benzene / 24 h / Heating

With hydrogenchloride; Sensitox (Rose Bengal polymer); oxygen; toluene-4-sulfonic acid; In tetrahydrofuran; dichloromethane; benzene;

DOI:10.1016/S0040-4039(01)90426-5

Reference yield:

4,5-Diphenyl-2-[12-(tetrahydro-pyran-2-yloxy)-dodecyl]-oxazole (411237-97-3) → 2-(12-hydroxydodecanyl)-4,5-diphenyloxazole (78812-87-0)

Guidance literature:

With hydrogenchloride; In tetrahydrofuran; at 60 ℃; for 3h; Yield given;

DOI:10.1016/S0040-4039(01)90426-5

upstream raw materials:

2-methyl-4,5-diphenyloxazole

2-[(11-iodoundecyl)oxy]tetrahydro-2H-pyran

Downstream raw materials:

2-(12-hydroxydodecanyl)-4,5-diphenyloxazole

N-benzoylbenzamide

N-Benzoyl-N-(13-hydroxy-tridecanoyl)-benzamide