14224-99-8

Basic information

• Product Name: 2-METHYL-4,5-DIPHENYLOXAZOLE
• Synonyms: 2-Methyl-4,5-diphenyl-1,3-oxazole;2-METHYL-4,5-DIPHENYLOXAZOLE;2-METHYL-4 5-DIPHENYLOXAZOLE 95%;2-METHYL-4,5-DIPHENYLOXAZOLE 95+%
• CAS NO: 14224-99-8
• Molecular Formula: C₁₆H₁₃NO
• Molecular Weight: 235.28
• Mol File: 14224-99-8.mol
• Article Data: 31

Chemical Properties

• Melting Point: 28 °C(lit.)
• Boiling Point: 214 °C17 mm Hg(lit.)
• Flash Point: >230 °F
• Appearance: /
• Density: 1.116 g/mL at 25 °C(lit.)
• Vapor Pressure: 5.66E-05mmHg at 25°C
• Refractive Index: n20/D 1.628(lit.)
• CAS DataBase Reference: 2-METHYL-4,5-DIPHENYLOXAZOLE(CAS DataBase Reference)
• NIST Chemistry Reference: 2-METHYL-4,5-DIPHENYLOXAZOLE(14224-99-8)
• EPA Substance Registry System: 2-METHYL-4,5-DIPHENYLOXAZOLE(14224-99-8)

Safety Data

• WGK Germany: 3
• Hazardous Substances Data: 14224-99-8(Hazardous Substances Data)

Usage

General Description

2-METHYL-4,5-DIPHENYLOXAZOLE is a chemical compound with the molecular formula C17H15NO. It is a heterocyclic aromatic compound that consists of a five-membered oxazole ring with two phenyl groups and a methyl group attached. 2-METHYL-4,5-DIPHENYLOXAZOLE is commonly used in the manufacturing of pharmaceuticals, agrochemicals, and dyes. It is also utilized in organic synthesis and as a fluorescent dye for biological staining and imaging applications. 2-METHYL-4,5-DIPHENYLOXAZOLE is known for its light-emitting properties and is used as a fluorophore in the field of research and development for biological and chemical analysis.

InChI:InChI=1/C16H13NO/c1-12-17-15(13-8-4-2-5-9-13)16(18-12)14-10-6-3-7-11-14/h2-11H,1H3

Upstream product

• 60-35-5 acetamide 
• 451-40-1 phenyl benzyl ketone 
• 127-19-5 N,N-dimethyl acetamide 
• 16483-98-0 2,3-diphenyl-2H-azirine 
• 103-84-4 Acetanilid 
• 79-16-3 N-methyl-acetamide 
• 119718-87-5 cyano(phenyl)methyl acetate 
• 98-80-6 phenylboronic acid 
• 365-01-5 2,2-difluoro-2-phenylacetophenone 
• 591-50-4 iodobenzene 
• 591-51-5 phenyllithium 
• 2248-46-6 ethyl 2,2-difluoro-2-phenylacetate 
• 1494-20-8 2,2-difluoro-1,2-diphenylethan-1-ol 
• 720-43-4 2-fluoro-1,2-diphenylethanone 

Downstream Products

• 2818-82-8 2-methyl-4,5-diphenyl-1H-imidazole 
• 21511-90-0 N-(1,2-diphenylethyl)acetamide 
• 101081-84-9 4,5-dichloro-4,5-diphenyl-2-trichloromethyl-4,5-dihydro-oxazole 
• 76346-85-5 3-(2-Methyl-4,5-diphenyloxazolyl)cyclohexan-1-one 
• 93953-47-0 2-(4-[1,3]Dioxolan-2-yl-butyl)-4,5-diphenyl-oxazole 
• 20662-96-8 2-n-pentyl-4,5-diphenyloxazole 
• 89004-09-1 2-(3-oxobutyl)-4,5-diphenyloxazole 
• 89004-10-4 2-(2-oxocyclohexyl)-4,5-diphenyloxazole 
• 93953-53-8 2-(3-[1,3]Dioxolan-2-yl-propyl)-4,5-diphenyl-oxazole 
• 411237-97-3 4,5-Diphenyl-2-[12-(tetrahydro-pyran-2-yloxy)-dodecyl]-oxazole 
• 78812-87-0 2-(12-hydroxydodecanyl)-4,5-diphenyloxazole 
• 78812-88-1 2-(13-hydroxytridecanyl)-4,5-diphenyloxazole 
• 78812-89-2 2-(13-hydroxytetradecanyl)-4,5-diphenyloxazole 
• 78812-90-5 2-(10-hydroxy-7-undecenyl)-4,5-diphenyloxazole 

Relevant articles and documents

A NEW SYNTHESIS OF OXAZOLES

Oxazoles are prepared from the ketoximes in a single pot sequence.

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Iron-Catalyzed Cycloaddition of Amides and 2,3-Diaryl-2 H-azirines to Access Oxazoles via C-N Bond Cleavage

A novel and efficient iron-catalyzed cycloaddition reaction using readily available 2,3-diaryl-2H-azirines and primary amides is reported. A wide range of trisubstituted oxazoles could be achieved in good yields with good functional group compatibility. In this transformation, two C-N bonds were cleaed and new C-N and C-O bonds were formed.

Divergent Palladium-Catalyzed Tandem Reaction of Cyanomethyl Benzoates with Arylboronic Acids: Synthesis of Oxazoles and Isocoumarins

A palladium-catalyzed tandem reaction of cyanomethyl benzoates with arylboronic acids has been achieved. Substitution at the 2-position of cyanomethyl benzoates was found to be crucial for the selective synthesis of oxazoles and isocoumarins. Cyanomethyl

Iodine(III)-Catalyzed Formal [2 + 2 + 1] Cycloaddition Reaction for Metal-Free Construction of Oxazoles

The iodine(III) catalyst, in situ generated from iodoarene as a precatalyst with m-CPBA and Tf2NH, promoted the metal-free [2 + 2 + 1] cycloaddition-type reactions of alkynes, nitriles, and oxygen atoms for the regioselective formations of 2,4-disubstituted and 2,4,5-trisubstituted oxazole. A first example of iodine catalysis for multicomponent reactions is represented.