4-amino-N-isobutylbenzamide

Base Information

• Chemical Name: 4-amino-N-isobutylbenzamide
• CAS No.: 38681-73-1
• Molecular Formula: C₁₁H₁₆N₂O
• Molecular Weight: 192.261
• Mol file: 38681-73-1.mol

Synonyms:4-amino-N-isobutylbenzamide

Chemical Property of 4-amino-N-isobutylbenzamide

Chemical Property:

Purity/Quality:

99% ^*data from raw suppliers

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

Useful:

Technology Process of 4-amino-N-isobutylbenzamide

There total 5 articles about 4-amino-N-isobutylbenzamide which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 100.0%

→ 4-amino-N-isobutylbenzamide (38681-73-1)

Guidance literature:

With palladium 10% on activated carbon; hydrogen; In ethanol; at 50 ℃; for 12h;

Reference yield: 67.0%

N-isobutyl-4-nitrobenzamide (2585-25-3) → 4-amino-N-isobutylbenzamide (38681-73-1)

Guidance literature:

With ammonium chloride; zinc; In water; acetone; at 20 ℃; for 0.0166667h;

DOI:10.1039/c9cc08296d

Reference yield:

isobutylamine (78-81-9) + 4-amino-benzoic acid (150-13-0,159246-81-8,8014-65-1) → 4-amino-N-isobutylbenzamide (38681-73-1)

Guidance literature:

With benzotriazol-1-ol; 1-ethyl-(3-(3-dimethylamino)propyl)-carbodiimide hydrochloride; N-ethyl-N,N-diisopropylamine; In dichloromethane; at 0 ℃; for 3h;

DOI:10.1021/jm070564e

upstream raw materials:

isobutylamine

4-amino-benzoic acid

2-nitrobenzamide

N-isobutyl-4-nitrobenzamide

Refernces

• 1、 Yuan, Zhengnan,Yang, Xiaoxiao,De La Cruz, Ladie Kimberly,Wang, Binghe. "Nitro reduction-based fluorescent probes for carbon monoxide require reactivity involving a ruthenium carbonyl moiety". supporting information. p. 2190 - 2193. Retrieved 2020/02/27.
• 2、 Xie, Hui,Ng, Danny,Savinov, Sergey N.,Dey, Barna,Kwong, Peter D.,Wyatt, Richard,Smith III, Amos B.,Hendrickson, Wayne A.. "Structure-activity relationships in the binding of chemically derivatized CD4 to gp120 from human immunodeficiency virus". . p. 4898 - 4908. Retrieved 2008/03/11.