biphenyl-4-yl(2-(4-methylbenzoyl)phenyl)methanone

Base Information

• Chemical Name: biphenyl-4-yl(2-(4-methylbenzoyl)phenyl)methanone
• CAS No.: 1276042-03-5
• Molecular Formula: C₂₇H₂₀O₂
• Molecular Weight: 376.455
• Mol file: 1276042-03-5.mol

Synonyms:biphenyl-4-yl(2-(4-methylbenzoyl)phenyl)methanone

Chemical Property of biphenyl-4-yl(2-(4-methylbenzoyl)phenyl)methanone

Chemical Property:

Purity/Quality:

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

Useful:

Technology Process of biphenyl-4-yl(2-(4-methylbenzoyl)phenyl)methanone

There total 7 articles about biphenyl-4-yl(2-(4-methylbenzoyl)phenyl)methanone which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 96.0%

C27H22O → biphenyl-4-yl(2-(4-methylbenzoyl)phenyl)methanone (1276042-03-5)

Guidance literature:

With lead(IV) tetraacetate; In tetrahydrofuran; at 50 ℃; for 0.5h;

DOI:10.1021/jo301410w

Reference yield:

C27H23N → biphenyl-4-yl(2-(4-methylbenzoyl)phenyl)methanone (1276042-03-5)

Guidance literature:

C₂₇H₂₃N; With oxygen; copper diacetate; In diethyl ether; N,N-dimethyl-formamide; at 80 ℃;

With hydrogenchloride; In diethyl ether; water; N,N-dimethyl-formamide; at 80 ℃;

DOI:10.1021/ol200425c

Reference yield:

2-(biphenyl-4-ylmethyl)benzonitrile (1276041-88-3) → biphenyl-4-yl(2-(4-methylbenzoyl)phenyl)methanone (1276042-03-5)

Guidance literature:

Multi-step reaction with 2 steps

1.1: diethyl ether / 2 h / 60 °C / Cooling; Sealed tube

2.1: oxygen; copper diacetate / diethyl ether; N,N-dimethyl-formamide / 80 °C

2.2: 80 °C

With oxygen; copper diacetate; In diethyl ether; N,N-dimethyl-formamide;

DOI:10.1021/ol200425c

upstream raw materials:

2-(biphenyl-4-ylmethyl)benzonitrile

4-biphenylboronic acid

2-(bromomethyl)benzonitrile

para-bromotoluene

Downstream raw materials:

C₃₇H₄₀O₄

2-phenyl-9-p-tolylanthracene