N-(7-Oxadecyl)deoxynojirimycin

Base Information

• Chemical Name: N-(7-Oxadecyl)deoxynojirimycin
• CAS No.: 160632-05-3
• Molecular Formula: C₁₅H₃₁NO₅
• Molecular Weight: 305.415
• Mol file: 160632-05-3.mol

Synonyms:3,4,5-Piperidinetriol,2-(hydroxymethyl)-1-(6-propoxyhexyl)-, [2R-(2a,3b,4a,5b)]-; N-7-Oxadecyldeoxynojirimycin; SP 116

Chemical Property of N-(7-Oxadecyl)deoxynojirimycin

Chemical Property:

• Vapor Pressure: 4.98E-11mmHg at 25°C
• Refractive Index: 1.52
• Boiling Point: 475.3°C at 760 mmHg
• PKA: 13.72±0.70(Predicted)
• Flash Point: 241.2°C
• PSA: 93.39000
• Density: 1.145g/cm³
• LogP: -0.32950
• Storage Temp.: Refrigerator, Under Inert Atmosphere

Purity/Quality:

95% ^*data from raw suppliers

N-(7-Oxadecyl)deoxynojirimycin ^*data from reagent suppliers

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

SDS file from LookChem

Useful:

• Uses: A inhibitor of glucosidase 1.

Technology Process of N-(7-Oxadecyl)deoxynojirimycin

There total 6 articles about N-(7-Oxadecyl)deoxynojirimycin which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 93.0%

N-(7-Oxadecyl)-2,3,4,6-tetra-O-benzyl-1-deoxynojirimycin (162398-47-2) → N-(7-oxadecyl)-1-deoxynojirimycin (160632-05-3)

Guidance literature:

With hydrogen; palladium on activated charcoal; In acetic acid; tert-butyl alcohol;

Reference yield: 85.0%

1,5-dideoxy-1,5-imino-D-glucitol (19130-96-2) + 6-propyloxy-1-hexanal → N-(7-oxadecyl)-1-deoxynojirimycin (160632-05-3)

Guidance literature:

With hydrogen; palladium dihydroxide; In ethanol;

Reference yield:

1,6-hexanediol (629-11-8) → N-(7-oxadecyl)-1-deoxynojirimycin (160632-05-3)

Guidance literature:

Multi-step reaction with 3 steps

1: KO-t-Bu / tetrahydrofuran

3: 93 percent / H₂ / 10percent Pd/C / 2-methyl-propan-2-ol; aq. acetic acid

With potassium tert-butylate; hydrogen; palladium on activated charcoal; In tetrahydrofuran; acetic acid; tert-butyl alcohol;

upstream raw materials:

1,5-dideoxy-1,5-imino-D-glucitol

N-(7-Oxadecyl)-2,3,4,6-tetra-O-benzyl-1-deoxynojirimycin

1,6-hexanediol

6-propyloxy-1-hexanol