Technology Process of N-(but-1-en-3-yl)-6-ethenyl-2-methoxy-N-p-toluenesulfonylaniline
There total 1 articles about N-(but-1-en-3-yl)-6-ethenyl-2-methoxy-N-p-toluenesulfonylaniline which
guide to synthetic route it.
The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:
synthetic route:
- Guidance literature:
-
With
triphenylphosphine; diethylazodicarboxylate;
In
tetrahydrofuran;
at 20 ℃;
for 2.5h;
DOI:10.1002/ejoc.200900520
- Guidance literature:
-
N-(but-1-en-3-yl)-6-ethenyl-2-methoxy-N-p-toluenesulfonylaniline;
With
carbonylchlorohydridotris(triphenylphosphine)ruthenium(II);
for 4h;
Reflux;
With
tricyclohexylphosphine[1,3-bis(2,4,6-trimethylphenyl)-4,5-dihydroimidazol-2-ylidine][benzylidene]ruthenium(II) dichloride;
for 3h;
Reflux;
DOI:10.1021/jm301084z
- Guidance literature:
-
Multi-step reaction with 4 steps
1.1: carbonylchlorohydridotris(triphenylphosphine)ruthenium(II) / 4 h / Reflux
1.2: 3 h / Reflux
2.1: potassium hydroxide / methanol / 4 h / Reflux
3.1: n-butyllithium; zinc(II) chloride / tetrahydrofuran; hexane; diethyl ether / 1 h / 0 - 20 °C
3.2: 15 h
4.1: potassium tert-butylate / tetrahydrofuran / 1 h / -78 °C
4.2: 3 h
With
carbonylchlorohydridotris(triphenylphosphine)ruthenium(II); n-butyllithium; potassium tert-butylate; potassium hydroxide; zinc(II) chloride;
In
tetrahydrofuran; methanol; diethyl ether; hexane;
DOI:10.1021/jm301084z
