(R)-N-[2-(tert-butyldiphenylsilyloxy)-1-(2-furyl)ethyl]-4-methylbenzenesulfonamide

Base Information

Chemical Name:(R)-N-[2-(tert-butyldiphenylsilyloxy)-1-(2-furyl)ethyl]-4-methylbenzenesulfonamide
CAS No.:1018811-53-4
Molecular Formula:C₂₉H₃₃NO₄SSi
Molecular Weight:519.737
Hs Code.:

Synonyms:(R)-N-[2-(tert-butyldiphenylsilyloxy)-1-(2-furyl)ethyl]-4-methylbenzenesulfonamide

Suppliers and Price of (R)-N-[2-(tert-butyldiphenylsilyloxy)-1-(2-furyl)ethyl]-4-methylbenzenesulfonamide

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Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

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Total 1 raw suppliers

Chemical Property of (R)-N-[2-(tert-butyldiphenylsilyloxy)-1-(2-furyl)ethyl]-4-methylbenzenesulfonamide

Chemical Property:

Purity/Quality:: 98% ^*data from raw suppliers

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Technology Process of (R)-N-[2-(tert-butyldiphenylsilyloxy)-1-(2-furyl)ethyl]-4-methylbenzenesulfonamide

There total 4 articles about (R)-N-[2-(tert-butyldiphenylsilyloxy)-1-(2-furyl)ethyl]-4-methylbenzenesulfonamide which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

: 124067-17-0
(2R) 1-<(t-butyldiphenylsilyl)oxy>-2-furanylethanol

: 1018811-53-4
(R)-N-[2-(tert-butyldiphenylsilyloxy)-1-(2-furyl)ethyl]-4-methylbenzenesulfonamide

Guidance literature:: Multi-step reaction with 5 steps

1: 75 percent / diethyl azodicarboxylate; PPh₃ / tetrahydrofuran / 1.5 h

2: 80 percent / NaOH / H₂O; methanol / 3 h / 20 °C

3: 78 percent / diphenylphosphoryl azide; 1,8-diazabicyclo[5.4.0]undec-7-ene / toluene / 2 h / 0 °C

4: hydrogen / Pd/C / ethyl acetate / 0.67 h / 750.08 Torr

5: 0.5 g / triethylamine / CH₂Cl₂ / 3 h / 20 °C

With sodium hydroxide; diphenylphosphoranyl azide; hydrogen; 1,8-diazabicyclo[5.4.0]undec-7-ene; triethylamine; triphenylphosphine; diethylazodicarboxylate; palladium on activated charcoal; In tetrahydrofuran; methanol; dichloromethane; water; ethyl acetate; toluene;
DOI:10.3390/12040735

Reference yield:

: 381164-66-5
(S)-2-(tert-butyldiphenylsilyloxy)-1-(furan-2-yl)ethanol

: 1018811-53-4
(R)-N-[2-(tert-butyldiphenylsilyloxy)-1-(2-furyl)ethyl]-4-methylbenzenesulfonamide

Guidance literature:: Multi-step reaction with 3 steps

1: 78 percent / diphenylphosphoryl azide; 1,8-diazabicyclo[5.4.0]undec-7-ene / toluene / 2 h / 0 °C

2: hydrogen / Pd/C / ethyl acetate / 0.67 h / 750.08 Torr

3: 0.5 g / triethylamine / CH₂Cl₂ / 3 h / 20 °C

With diphenylphosphoranyl azide; hydrogen; 1,8-diazabicyclo[5.4.0]undec-7-ene; triethylamine; palladium on activated charcoal; In dichloromethane; ethyl acetate; toluene;
DOI:10.3390/12040735

Reference yield:

: 381164-65-4
(S)-2-(tert-butyldiphenylsilyloxy)-1-(2-furyl)ethyl benzoate

: 1018811-53-4
(R)-N-[2-(tert-butyldiphenylsilyloxy)-1-(2-furyl)ethyl]-4-methylbenzenesulfonamide

Guidance literature:: Multi-step reaction with 4 steps

1: 80 percent / NaOH / H₂O; methanol / 3 h / 20 °C

2: 78 percent / diphenylphosphoryl azide; 1,8-diazabicyclo[5.4.0]undec-7-ene / toluene / 2 h / 0 °C

3: hydrogen / Pd/C / ethyl acetate / 0.67 h / 750.08 Torr

4: 0.5 g / triethylamine / CH₂Cl₂ / 3 h / 20 °C

With sodium hydroxide; diphenylphosphoranyl azide; hydrogen; 1,8-diazabicyclo[5.4.0]undec-7-ene; triethylamine; palladium on activated charcoal; In methanol; dichloromethane; water; ethyl acetate; toluene;
DOI:10.3390/12040735