Methyl 2-amino-4-(4-fluorophenyl)-6-isopropylpyrimidine-5-carboxylate

Base Information

Chemical Name:Methyl 2-amino-4-(4-fluorophenyl)-6-isopropylpyrimidine-5-carboxylate
CAS No.:160009-37-0
Molecular Formula:C15H16 F N3 O2
Molecular Weight:289.309
Hs Code.:2933599090
DSSTox Substance ID:DTXSID801142586
Mol file:160009-37-0.mol

Synonyms:160009-37-0;Methyl 2-amino-4-(4-fluorophenyl)-6-isopropylpyrimidine-5-carboxylate;methyl 2-amino-4-(4-fluorophenyl)-6-propan-2-ylpyrimidine-5-carboxylate;methyl 2-amino-4-(4-fluorophenyl)-6-isopropyl-pyrimidine-5-carboxylate;SCHEMBL1752471;DTXSID801142586;AKOS000280350;SB60076;Methyl2-amino-4-(4-fluorophenyl)-6-isopropylpyrimidine-5-carboxylate;Methyl 2-amino-4-(4-fluorophenyl)-6-(1-methylethyl)-5-pyrimidinecarboxylate

Suppliers and Price of Methyl 2-amino-4-(4-fluorophenyl)-6-isopropylpyrimidine-5-carboxylate

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

TRC
Methyl2-Amino-4-(4-fluorophenyl)-6-isopropylpyrimidine-5-carboxylate
5g
$ 1320.00

TRC
Methyl2-Amino-4-(4-fluorophenyl)-6-isopropylpyrimidine-5-carboxylate
500mg
$ 165.00

Medical Isotopes, Inc.
Methyl2-Amino-4-(4-fluorophenyl)-6-isopropylpyrimidine-5-carboxylate
500 mg
$ 650.00

Crysdot
Methyl2-amino-4-(4-fluorophenyl)-6-isopropylpyrimidine-5-carboxylate 95+%
1g
$ 880.00

Chemenu
methyl2-amino-4-(4-fluorophenyl)-6-isopropylpyrimidine-5-carboxylate 95%
1g
$ 830.00

Alichem
Methyl2-amino-4-(4-fluorophenyl)-6-isopropylpyrimidine-5-carboxylate
1g
$ 771.12

Total 3 raw suppliers

Chemical Property of Methyl 2-amino-4-(4-fluorophenyl)-6-isopropylpyrimidine-5-carboxylate

Chemical Property:

Boiling Point:498.1±55.0 °C(Predicted)
PKA:1.98±0.10(Predicted)
PSA：78.83000
Density:1.227±0.06 g/cm3(Predicted)
LogP:2.70500
Storage Temp.:2-8°C
XLogP3:2.6
Hydrogen Bond Donor Count:1
Hydrogen Bond Acceptor Count:6
Rotatable Bond Count:4
Exact Mass:289.12265492
Heavy Atom Count:21
Complexity:359

Purity/Quality:

98%min ^*data from raw suppliers

Methyl2-Amino-4-(4-fluorophenyl)-6-isopropylpyrimidine-5-carboxylate ^*data from reagent suppliers

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:: SDS file from LookChem

Useful:

Canonical SMILES:CC(C)C1=NC(=NC(=C1C(=O)OC)C2=CC=C(C=C2)F)N
Uses Methyl 2-Amino-4-(4-fluorophenyl)-6-isopropylpyrimidine-5-carboxylate is an intermediate in the synthesis of Rosuvastatin-d3 Sodium Salt (R700501), the labeled analogue of Rosuvastatin (R700500), a selective, competitive HMG-CoA reductase inhibitor. Antilipemic.

Technology Process of Methyl 2-amino-4-(4-fluorophenyl)-6-isopropylpyrimidine-5-carboxylate

There total 4 articles about Methyl 2-amino-4-(4-fluorophenyl)-6-isopropylpyrimidine-5-carboxylate which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 89.0%