(2S)-N-benzyl-N-(2-{[tert-butyl(dimethyl)silyl]oxy}propyl)-2,6-dichloronicotinamide

Base Information

Chemical Name:(2S)-N-benzyl-N-(2-{[tert-butyl(dimethyl)silyl]oxy}propyl)-2,6-dichloronicotinamide
CAS No.:956434-50-7
Molecular Formula:C₂₂H₃₀Cl₂N₂O₂Si
Molecular Weight:453.484
Hs Code.:

Synonyms:(2S)-N-benzyl-N-(2-{[tert-butyl(dimethyl)silyl]oxy}propyl)-2,6-dichloronicotinamide

Suppliers and Price of (2S)-N-benzyl-N-(2-{[tert-butyl(dimethyl)silyl]oxy}propyl)-2,6-dichloronicotinamide

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Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

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Chemical Property of (2S)-N-benzyl-N-(2-{[tert-butyl(dimethyl)silyl]oxy}propyl)-2,6-dichloronicotinamide

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Technology Process of (2S)-N-benzyl-N-(2-{[tert-butyl(dimethyl)silyl]oxy}propyl)-2,6-dichloronicotinamide

There total 1 articles about (2S)-N-benzyl-N-(2-{[tert-butyl(dimethyl)silyl]oxy}propyl)-2,6-dichloronicotinamide which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 92.0%

: 2942-59-8
2-chloronicotinic acid

: 956434-49-4
(2S)-N-benzyl-2-{[tert-butyl(dimethyl)silyl]oxy}propan-1-amine

: 956434-50-7
(2S)-N-benzyl-N-(2-{[tert-butyl(dimethyl)silyl]oxy}propyl)-2,6-dichloronicotinamide

Guidance literature:: 2-chloronicotinic acid; With oxalyl dichloride; N,N-dimethyl-formamide; In toluene; at 20 ℃; for 1h;

(2S)-N-benzyl-2-{[tert-butyl(dimethyl)silyl]oxy}propan-1-amine; With triethylamine; In tetrahydrofuran; at 0 - 20 ℃; for 2h;