(S)-7-(1-(4-fluorophenyl)ethyl)-3-(3-methoxy-4-(4-methyl-1H-imidazol-1-yl)phenyl)-5-((4-methoxybenzyloxy)methyl)-7H-pyrazolo[3,4-b]pyridine

Base Information

Chemical Name:(S)-7-(1-(4-fluorophenyl)ethyl)-3-(3-methoxy-4-(4-methyl-1H-imidazol-1-yl)phenyl)-5-((4-methoxybenzyloxy)methyl)-7H-pyrazolo[3,4-b]pyridine
CAS No.:1160358-02-0
Molecular Formula:C₃₄H₃₂FN₅O₃
Molecular Weight:577.658
Hs Code.:

Synonyms:(S)-7-(1-(4-fluorophenyl)ethyl)-3-(3-methoxy-4-(4-methyl-1H-imidazol-1-yl)phenyl)-5-((4-methoxybenzyloxy)methyl)-7H-pyrazolo[3,4-b]pyridine

Suppliers and Price of (S)-7-(1-(4-fluorophenyl)ethyl)-3-(3-methoxy-4-(4-methyl-1H-imidazol-1-yl)phenyl)-5-((4-methoxybenzyloxy)methyl)-7H-pyrazolo[3,4-b]pyridine

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

Total 0 raw suppliers

Chemical Property of (S)-7-(1-(4-fluorophenyl)ethyl)-3-(3-methoxy-4-(4-methyl-1H-imidazol-1-yl)phenyl)-5-((4-methoxybenzyloxy)methyl)-7H-pyrazolo[3,4-b]pyridine

Chemical Property:

Purity/Quality:

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:

Useful:

Technology Process of (S)-7-(1-(4-fluorophenyl)ethyl)-3-(3-methoxy-4-(4-methyl-1H-imidazol-1-yl)phenyl)-5-((4-methoxybenzyloxy)methyl)-7H-pyrazolo[3,4-b]pyridine

There total 11 articles about (S)-7-(1-(4-fluorophenyl)ethyl)-3-(3-methoxy-4-(4-methyl-1H-imidazol-1-yl)phenyl)-5-((4-methoxybenzyloxy)methyl)-7H-pyrazolo[3,4-b]pyridine which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 54.0%

: 1128103-59-2
C₃₄H₃₄FN₅O₄

: 1160358-02-0
(S)-7-(1-(4-fluorophenyl)ethyl)-3-(3-methoxy-4-(4-methyl-1H-imidazol-1-yl)phenyl)-5-((4-methoxybenzyloxy)methyl)-7H-pyrazolo[3,4-b]pyridine

Guidance literature:: With pyridine; trichlorophosphate; at 50 ℃; for 2h; Inert atmosphere;
DOI:10.1021/ml2000438

Reference yield:

: 1128103-55-8
C₃₄H₃₄FN₃O₅

: 1160358-02-0
(S)-7-(1-(4-fluorophenyl)ethyl)-3-(3-methoxy-4-(4-methyl-1H-imidazol-1-yl)phenyl)-5-((4-methoxybenzyloxy)methyl)-7H-pyrazolo[3,4-b]pyridine

: 1160358-03-1
C₃₄H₃₁ClFN₅O₃

Guidance literature:: C₃₄H₃₄FN₃O₅; With Dess-Martin periodane; In dichloromethane; at 20 ℃; for 16h;

With ammonium chloride; In dichloromethane;

Reference yield:

: 1128105-86-1
C₁₅H₁₃BrFNO₃

: 1160358-02-0
(S)-7-(1-(4-fluorophenyl)ethyl)-3-(3-methoxy-4-(4-methyl-1H-imidazol-1-yl)phenyl)-5-((4-methoxybenzyloxy)methyl)-7H-pyrazolo[3,4-b]pyridine

Guidance literature:: Multi-step reaction with 8 steps

1.1: water; sodium hydroxide / methanol / 16 h / 20 °C / Inert atmosphere

2.1: pyridine; trifluoro-[1,3,5]triazine / dichloromethane / -10 - 20 °C / Inert atmosphere

3.1: sodium tetrahydroborate / methanol; dichloromethane / 2 h / 20 °C / Inert atmosphere

4.1: sodium hydride / tetrahydrofuran / 0.5 h / Inert atmosphere

4.2: 4 h / 20 °C / Inert atmosphere

5.1: TurboGrignard / tetrahydrofuran / 0.5 h / Inert atmosphere

5.2: 16 h / 20 °C / Inert atmosphere

6.1: Dess-Martin periodane / dichloromethane / 16 h / 20 °C / Inert atmosphere

7.1: hydrazine hydrate / ethanol / 2 h / 80 °C / Inert atmosphere

8.1: pyridine; trichlorophosphate / 2 h / 50 °C / Inert atmosphere

With pyridine; sodium tetrahydroborate; TurboGrignard; trifluoro-[1,3,5]triazine; water; sodium hydride; Dess-Martin periodane; hydrazine hydrate; sodium hydroxide; trichlorophosphate; In tetrahydrofuran; methanol; ethanol; dichloromethane; 6.1: Dess-Martin oxidation;
DOI:10.1021/ml2000438