Ethanone, 1-[4-(1,2-propadienyl)phenyl]- (9CI)

Base Information

• Chemical Name: Ethanone, 1-[4-(1,2-propadienyl)phenyl]- (9CI)
• CAS No.: 159527-72-7
• Molecular Formula: C11H10 O
• Molecular Weight: 158.2
• Mol file: 159527-72-7.mol

Synonyms:Ethanone,1-[4-(1,2-propadienyl)phenyl]- (9CI); (4-Acetylphenyl)allene;1-[4-(1,2-Propadienyl)phenyl]ethanone; 4'-Acetylphenylallene

Chemical Property of Ethanone, 1-[4-(1,2-propadienyl)phenyl]- (9CI)

Chemical Property:

• Boiling Point: 301.0±12.0 °C(Predicted)
• PSA: 17.07000
• Density: 0.976±0.06 g/cm3(Predicted)
• LogP: 2.68730

Purity/Quality:

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

SDS file from LookChem

Useful:

Technology Process of Ethanone, 1-[4-(1,2-propadienyl)phenyl]- (9CI)

There total 8 articles about Ethanone, 1-[4-(1,2-propadienyl)phenyl]- (9CI) which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 87.0%

4-Iodoacetophenone (13329-40-3) + propargyl bromide (106-96-7) → 1-(4-(1,2-propadienyl)phenyl)-1-ethanone (159527-72-7)

Guidance literature:

With indium; lithium chloride; tetrakis(triphenylphosphine) palladium⁽⁰⁾; In N,N-dimethyl-formamide; at 100 ℃;

DOI:10.1002/1521-3773(20021018)41:20<3901::AID-ANIE3901>3.0.CO;2-S

Reference yield: 79.0%

1-[4-(3-dicyclohexylamino-prop-1-ynyl)-phenyl]-ethanone → 1-(4-(1,2-propadienyl)phenyl)-1-ethanone (159527-72-7)

Guidance literature:

With 1,2-bis(di(pentafluorophenyl)phosphino)ethane; tris(dibenzylideneacetone)dipalladium⁽⁰⁾ chloroform complex; In chloroform; at 20 ℃; for 96h;

DOI:10.1016/j.tetlet.2005.09.169

Reference yield: 74.0%

4-Iodoacetophenone (13329-40-3) + allenyltributylstannane (53915-69-8) → 1-(4-(1,2-propadienyl)phenyl)-1-ethanone (159527-72-7)

Guidance literature:

With tetrakis(triphenylphosphine) palladium⁽⁰⁾; lithium chloride; In N,N-dimethyl-formamide; at 25 ℃; for 3h;

DOI:10.1016/S0040-4020(03)00516-7

upstream raw materials:

4-acetylphenyl mesylate

allenyltributylstannane

4-Iodoacetophenone

propargyl bromide

Downstream raw materials:

(E)-1,1'-(4,4'-(5-oxocyclopent-3-ene-3-yl-1-ylidene)bis(methylene)bis(4,1-phenylene))diethanone

(E)-1,1'-(4,4'-(4-oxocyclopent-2-ene-2-yl-1-ylidene)bis(methylene)bis(4,1-phenylene))diethanone

CH₃COC₆H₄CHC(Si(CH₃)3)(CH₂Sn(C₄H₉)3)