2-oxo-2-(1,2-distearoyl-3-rac-glycero)-5-benzyloxy-1,3,2-dioxaphosphorinane

Base Information

• Chemical Name: 2-oxo-2-(1,2-distearoyl-3-rac-glycero)-5-benzyloxy-1,3,2-dioxaphosphorinane
• CAS No.: 79635-18-0
• Molecular Formula: C₄₉H₈₇O₉P
• Molecular Weight: 851.198
• Mol file: 79635-18-0.mol

Synonyms:2-oxo-2-(1,2-distearoyl-3-rac-glycero)-5-benzyloxy-1,3,2-dioxaphosphorinane

Chemical Property of 2-oxo-2-(1,2-distearoyl-3-rac-glycero)-5-benzyloxy-1,3,2-dioxaphosphorinane

Chemical Property:

Purity/Quality:

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

Useful:

Technology Process of 2-oxo-2-(1,2-distearoyl-3-rac-glycero)-5-benzyloxy-1,3,2-dioxaphosphorinane

There total 9 articles about 2-oxo-2-(1,2-distearoyl-3-rac-glycero)-5-benzyloxy-1,3,2-dioxaphosphorinane which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 40.0%

2-oxo-2-(1,2-O,O-isopropylidene-3-rac-glycero)-5-benzyloxy-1,3,2-dioxaphosphorinane (64528-51-4) + Stearoyl chloride (112-76-5) → 2-oxo-2-(1,2-distearoyl-3-rac-glycero)-5-benzyloxy-1,3,2-dioxaphosphorinane (79635-18-0)

Guidance literature:

With zinc(II) chloride; In chloroform; at 20 ℃; for 1h;

Reference yield:

Octadecanoic acid 2-(5-benzyloxy-[1,3,2]dioxaphosphinan-2-yloxy)-1-octadecanoyloxymethyl-ethyl ester (80197-14-4) → 2-oxo-2-(1,2-distearoyl-3-rac-glycero)-5-benzyloxy-1,3,2-dioxaphosphorinane (79635-18-0)

Guidance literature:

With iodosylbenzene; In benzene; at 20 ℃; for 6h;

Reference yield:

2-O-benzylglycerol (14690-00-7) → 2-oxo-2-(1,2-distearoyl-3-rac-glycero)-5-benzyloxy-1,3,2-dioxaphosphorinane (79635-18-0)

Guidance literature:

Multi-step reaction with 3 steps

1: 65.1 percent / 3 h / 120 °C / 487.5 Torr

2: 1.28 g / benzene / 3 h / 135 - 140 °C / 300.02 Torr

3: 0.89 g / iodosobenzene / benzene / 6 h / 20 °C

With iodosylbenzene; In benzene;

upstream raw materials:

Octadecanoic acid 2-(5-benzyloxy-[1,3,2]dioxaphosphinan-2-yloxy)-1-octadecanoyloxymethyl-ethyl ester

2-oxo-2-(1,2-O,O-isopropylidene-3-rac-glycero)-5-benzyloxy-1,3,2-dioxaphosphorinane

Stearoyl chloride

2-O-benzylglycerol

Downstream raw materials:

1,2-distearoyl-3-rac-glycerophosphoryl-2'-benzyloxyhomocholine