(S,E)-2,4,6-trimethyl-N-(4-methylbenzylidene)benzenesulfinamide

Base Information

• Chemical Name: (S,E)-2,4,6-trimethyl-N-(4-methylbenzylidene)benzenesulfinamide
• CAS No.: 1251919-32-0
• Molecular Formula: C₁₇H₁₉NOS
• Molecular Weight: 285.41
• Mol file: 1251919-32-0.mol

Synonyms:(S,E)-2,4,6-trimethyl-N-(4-methylbenzylidene)benzenesulfinamide

Chemical Property of (S,E)-2,4,6-trimethyl-N-(4-methylbenzylidene)benzenesulfinamide

Chemical Property:

Purity/Quality:

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

Useful:

Technology Process of (S,E)-2,4,6-trimethyl-N-(4-methylbenzylidene)benzenesulfinamide

There total 1 articles about (S,E)-2,4,6-trimethyl-N-(4-methylbenzylidene)benzenesulfinamide which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 68.0%

4-methyl-benzaldehyde (104-87-0) + (S)-(+)-2,4,6-trimethylbenzenesulfinamide (607729-50-0) → (S,E)-2,4,6-trimethyl-N-(4-methylbenzylidene)benzenesulfinamide (1251919-32-0)

Guidance literature:

With titanium(IV) tetraethanolate; In dichloromethane; Sealed tube; Reflux;

DOI:10.1039/c7cc03724d

Reference yield: 59.0%

(S,E)-2,4,6-trimethyl-N-(4-methylbenzylidene)benzenesulfinamide (1251919-32-0) + 1,3-dioxoisoindolin-2-yl isobutyrate (1631179-23-1) → (S)-2,4,6-trimethyl-N-((S)-2-methyl-1-(p-tolyl)propyl)benzenesulfinamide

Guidance literature:

With tris[2-phenylpyridinato-C₂,N]iridium(III); diethyl 2,6-dimethyl-1,4-dihydropyridine-3,5-dicarboxylate; N-ethyl-N,N-diisopropylamine; In dimethyl sulfoxide; at 20 ℃; for 40h; diastereoselective reaction; Sealed tube; Inert atmosphere; Irradiation;

DOI:10.1039/c7cc03724d

Reference yield:

4,4,5,5-tetramethyl-1,3-dioxolane (5660-63-9) + (S,E)-2,4,6-trimethyl-N-(4-methylbenzylidene)benzenesulfinamide (1251919-32-0) → C24H33NO3S

Guidance literature:

4,4,5,5-tetramethyl-1,3-dioxolane; (S,E)-2,4,6-trimethyl-N-(4-methylbenzylidene)benzenesulfinamide; With boron trifluoride diethyl etherate; dimethyl zinc(II); In hexane; at 20 ℃; Inert atmosphere;

In hexane; at 20 ℃; stereoselective reaction;

DOI:10.1248/cpb.58.265

upstream raw materials:

4-methyl-benzaldehyde

(S)-(+)-2,4,6-trimethylbenzenesulfinamide