C₂₀H₃₄O₄Si

Base Information

• Chemical Name: C₂₀H₃₄O₄Si
• CAS No.: 1349725-43-4
• Molecular Formula: C₂₀H₃₄O₄Si
• Molecular Weight: 366.573
• Mol file: 1349725-43-4.mol

Synonyms:C₂₀H₃₄O₄Si

Chemical Property of C₂₀H₃₄O₄Si

Chemical Property:

Purity/Quality:

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

Useful:

Technology Process of C₂₀H₃₄O₄Si

There total 8 articles about C₂₀H₃₄O₄Si which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 68.0%

C14H20O4 (1349725-40-1) + tert-butyldimethylsilyl chloride (18162-48-6) → C20H34O4Si (1349725-43-4)

Guidance literature:

With 1H-imidazole; In dichloromethane; at 0 - 20 ℃; for 12h;

DOI:10.1002/asia.201100429

Reference yield:

C16H22O4 (213692-93-4) → C20H34O4Si (1349725-43-4)

Guidance literature:

Multi-step reaction with 5 steps

1: diisobutylaluminium hydride / dichloromethane; toluene / 1 h / -78 °C

2: AD-mix α; methanesulfonamide / water; tert-butyl alcohol / 24 h / 0 °C

3: pyridine; dmap / 0 °C

4: potassium carbonate / methanol / 0 - 20 °C

5: 1H-imidazole / dichloromethane / 12 h / 0 - 20 °C

With pyridine; 1H-imidazole; dmap; methanesulfonamide; AD-mix α; diisobutylaluminium hydride; potassium carbonate; In methanol; dichloromethane; water; toluene; tert-butyl alcohol; 2: Sharpless dihydroxylation;

DOI:10.1002/asia.201100429

Reference yield:

C14H20O3 (831228-09-2) → C20H34O4Si (1349725-43-4)

Guidance literature:

Multi-step reaction with 4 steps

1: AD-mix α; methanesulfonamide / water; tert-butyl alcohol / 24 h / 0 °C

2: pyridine; dmap / 0 °C

3: potassium carbonate / methanol / 0 - 20 °C

4: 1H-imidazole / dichloromethane / 12 h / 0 - 20 °C

With pyridine; 1H-imidazole; dmap; methanesulfonamide; AD-mix α; potassium carbonate; In methanol; dichloromethane; water; tert-butyl alcohol; 1: Sharpless dihydroxylation;

DOI:10.1002/asia.201100429

upstream raw materials:

C₁₆H₂₂O₄

C₁₄H₂₀O₃

C₂₁H₂₈O₇S

C₁₄H₂₀O₄

Downstream raw materials:

C₂₀H₃₄O₃Si

C₂₁H₃₆O₄Si