N-(S)-[3-[4-(3,4-dihydro-(1H)-isoquinolin-2-yl)-3-fluorophenyl]-2-oxo-oxazolidin-5-yl]methylamine

Base Information

Chemical Name:N-(S)-[3-[4-(3,4-dihydro-(1H)-isoquinolin-2-yl)-3-fluorophenyl]-2-oxo-oxazolidin-5-yl]methylamine
CAS No.:449175-29-5
Molecular Formula:C₁₉H₂₀FN₃O₂
Molecular Weight:341.385
Hs Code.:

Synonyms:N-(S)-[3-[4-(3,4-dihydro-(1H)-isoquinolin-2-yl)-3-fluorophenyl]-2-oxo-oxazolidin-5-yl]methylamine

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Chemical Property of N-(S)-[3-[4-(3,4-dihydro-(1H)-isoquinolin-2-yl)-3-fluorophenyl]-2-oxo-oxazolidin-5-yl]methylamine

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Technology Process of N-(S)-[3-[4-(3,4-dihydro-(1H)-isoquinolin-2-yl)-3-fluorophenyl]-2-oxo-oxazolidin-5-yl]methylamine

There total 1 articles about N-(S)-[3-[4-(3,4-dihydro-(1H)-isoquinolin-2-yl)-3-fluorophenyl]-2-oxo-oxazolidin-5-yl]methylamine which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

: (R)-[3-[4-(3,4-dihydro-(1H)-isoquinolin-2-yl)-3-fluorophenyl]-2-oxo-oxazolidin-5-yl]methylazide

: 449175-29-5
N-(S)-[3-[4-(3,4-dihydro-(1H)-isoquinolin-2-yl)-3-fluorophenyl]-2-oxo-oxazolidin-5-yl]methylamine

Guidance literature:: With hydrogen; palladium 10% on activated carbon; In ethyl acetate; at 20 ℃;

Reference yield: 77.0%

: 449175-29-5
N-(S)-[3-[4-(3,4-dihydro-(1H)-isoquinolin-2-yl)-3-fluorophenyl]-2-oxo-oxazolidin-5-yl]methylamine

: 24065-33-6
5-Chlorothiophene-2-carboxylic acid

: 637027-49-7
N-(S)-[3-[4-(3,4-dihydro-(1H)-isoquinolin-2-yl)-3-fluorophenyl]-2-oxo-oxazolidin-5-ylmethyl](5-chlorothiophen-2-yl)carbonylamine

Guidance literature:: 5-Chlorothiophene-2-carboxylic acid; With 1-hydroxy-pyrrolidine-2,5-dione; dicyclohexyl-carbodiimide; In 1,4-dioxane; for 6h;

N-(S)-[3-[4-(3,4-dihydro-(1H)-isoquinolin-2-yl)-3-fluorophenyl]-2-oxo-oxazolidin-5-yl]methylamine; In 1,4-dioxane; at 20 ℃;