methyl 1-chloromethylcyclohexanecarboxylate

Base Information

• Chemical Name: methyl 1-chloromethylcyclohexanecarboxylate
• CAS No.: 57539-95-4
• Molecular Formula: C₉H₁₅ClO₂
• Molecular Weight: 190.67
• Mol file: 57539-95-4.mol

Synonyms:methyl 1-chloromethylcyclohexanecarboxylate

Chemical Property of methyl 1-chloromethylcyclohexanecarboxylate

Chemical Property:

Purity/Quality:

Safty Information:

• Pictogram(s):  
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MSDS Files:

Useful:

Technology Process of methyl 1-chloromethylcyclohexanecarboxylate

There total 4 articles about methyl 1-chloromethylcyclohexanecarboxylate which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 65.3%

→ methyl 1-chloromethylcyclohexanecarboxylate (57539-95-4)

Guidance literature:

Reference yield:

methyl cyclohexylcarboxylate (4630-82-4) + Chloroiodomethane (593-71-5) → methyl 1-chloromethylcyclohexanecarboxylate (57539-95-4)

Guidance literature:

methyl cyclohexylcarboxylate; With lithium diisopropyl amide; In tetrahydrofuran; at -78 ℃; for 1h;

Chloroiodomethane; In tetrahydrofuran; at -78 ℃; for 3h;

DOI:10.1021/acs.orglett.6b00289

Reference yield:

2,2-dichloro-1-cyclohexylethanone (39140-53-9) + sodium methylate (124-41-4) → methyl 1-chloromethylcyclohexanecarboxylate (57539-95-4)

Guidance literature:

In methanol;

DOI:10.1016/0040-4020(75)80198-0

upstream raw materials:

2,2-dichloro-1-cyclohexylethanone

sodium methylate

2-chloro-1-(1-chlorocyclohexyl)ethanone

methyl cyclohexylcarboxylate