(S)-2-((R)-2-CHLOROPROPANAMIDO)-4-CARBAMOYLBUTANOIC ACID

Base Information

• Chemical Name: (S)-2-((R)-2-CHLOROPROPANAMIDO)-4-CARBAMOYLBUTANOIC ACID
• CAS No.: 159141-33-0
• Molecular Formula: C₈H₁₃ClN₂O₄
• Molecular Weight: 236.655
• Hs Code.: 2924199090
• Mol file: 159141-33-0.mol

Synonyms:L-Glutamine, N²-(2-chloro-1-oxopropyl)-, (R)-;

Chemical Property of (S)-2-((R)-2-CHLOROPROPANAMIDO)-4-CARBAMOYLBUTANOIC ACID

Chemical Property:

• Boiling Point: 600.46 °C at 760 mmHg
• PKA: 3.09±0.10(Predicted)
• Flash Point: 316.947 °C
• PSA: 109.49000
• Density: 1.359 g/cm³
• LogP: 0.53980
• Storage Temp.: 2-8°C

Purity/Quality:

98%,99%, ^*data from raw suppliers

(S)-5-Amino-2-((R)-2-chloropropanamido)-5-oxopentanoic acid 95+% ^*data from reagent suppliers

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

SDS file from LookChem

Useful:

Technology Process of (S)-2-((R)-2-CHLOROPROPANAMIDO)-4-CARBAMOYLBUTANOIC ACID

There total 1 articles about (S)-2-((R)-2-CHLOROPROPANAMIDO)-4-CARBAMOYLBUTANOIC ACID which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

(R)-(-)-2-chloropropionyl chloride (70110-25-7) + L-glutamine (56-85-9,26700-71-0) → 2-chloropropionyl-L-glutamine (159141-33-0)

Guidance literature:

With sodium hydroxide;

DOI:10.1021/op000094x

Reference yield:

N-(α-chloro)propionyl-L-glutamine (159141-33-0) → alanylglutamine (39537-23-0,281660-34-2,656221-79-3,205252-36-4)

Guidance literature:

With ammonium hydroxide; In water; at 60 ℃; under 1500.15 Torr;

Reference yield:

2-chloropropionyl-L-glutamine (159141-33-0) → alanylglutamine (39537-23-0,281660-34-2,656221-79-3,205252-36-4)

Guidance literature:

With ammonia; In water;

DOI:10.1021/op000094x

upstream raw materials:

(R)-(-)-2-chloropropionyl chloride

L-glutamine

Downstream raw materials:

alanylglutamine

alanyl-glutamine

Refernces

• 1、 -. "Production process of chloropropionyl glutamine". Paragraph 0027-0029; 0032-0035. . Retrieved 2020/03/09.