benzyl N^β-(benzyloxycarbonyl)-N^α-<(RS)-α-(methoxycarbonyl)-β-phenylpropionyl>-L-α,β-diaminopropionate

Base Information

• Chemical Name: benzyl N^β-(benzyloxycarbonyl)-N^α-<(RS)-α-(methoxycarbonyl)-β-phenylpropionyl>-L-α,β-diaminopropionate
• CAS No.: 72594-83-3
• Molecular Formula: C₂₉H₃₀N₂O₇
• Molecular Weight: 518.566
• Mol file: 72594-83-3.mol

Synonyms:benzyl N^β-(benzyloxycarbonyl)-N^α-<(RS)-α-(methoxycarbonyl)-β-phenylpropionyl>-L-α,β-diaminopropionate

Chemical Property of benzyl N^β-(benzyloxycarbonyl)-N^α-<(RS)-α-(methoxycarbonyl)-β-phenylpropionyl>-L-α,β-diaminopropionate

Chemical Property:

Purity/Quality:

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

Useful:

Technology Process of benzyl N^β-(benzyloxycarbonyl)-N^α-<(RS)-α-(methoxycarbonyl)-β-phenylpropionyl>-L-α,β-diaminopropionate

There total 1 articles about benzyl N^β-(benzyloxycarbonyl)-N^α-<(RS)-α-(methoxycarbonyl)-β-phenylpropionyl>-L-α,β-diaminopropionate which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 76.0%

2-benzyl-3-methoxy-3-oxopropanoic acid (54561-75-0) + benzyl Nβ-(benzyloxycarbonyl)-L-α,β-diaminopropionate → benzyl Nβ-(benzyloxycarbonyl)-Nα-<(RS)-α-(methoxycarbonyl)-β-phenylpropionyl>-L-α,β-diaminopropionate (72594-83-3)

Guidance literature:

With dicyclohexyl-carbodiimide; In dichloromethane; at 0 - 20 ℃;

DOI:10.1021/jm00178a012

Reference yield:

benzyl Nβ-(benzyloxycarbonyl)-Nα-<(RS)-α-(methoxycarbonyl)-β-phenylpropionyl>-L-α,β-diaminopropionate (72594-83-3) → Nα-<(RS)-α-(methoxycarbonyl)-β-phenylpropionyl>-L-α,β-diaminopropionic acid (72594-79-7)

Guidance literature:

With hydrogen; palladium on activated charcoal; In methanol; water; acetic acid; for 4h; under 2068.6 Torr;

DOI:10.1021/jm00178a012

upstream raw materials:

2-benzyl-3-methoxy-3-oxopropanoic acid

Downstream raw materials:

N^α-<(RS)-α-(methoxycarbonyl)-β-phenylpropionyl>-L-α,β-diaminopropionic acid