Technology Process of C19H26ClNO3
There total 5 articles about C19H26ClNO3 which
guide to synthetic route it.
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synthetic route:
- Guidance literature:
-
C21H30ClNO3;
With
Grubbs catalyst first generation;
In
dichloromethane;
at 20 ℃;
for 2h;
With
dimethyl sulfoxide;
at 20 ℃;
for 12h;
DOI:10.3987/COM-10-S(E)76
- Guidance literature:
-
Multi-step reaction with 5 steps
1.1: sodium hydride / tetrahydrofuran; N,N-dimethyl-formamide / 15 h / 0 - 20 °C
2.1: 2,3-dicyano-5,6-dichloro-p-benzoquinone / dichloromethane / 3 h / 0 °C / pH 8 / aq. buffer
3.1: lithium hexamethyldisilazane / tetrahydrofuran / 2 h / -78 - 0 °C
4.1: tetrachloromethane; 1-methylcyclohex-1-ene; TOP / toluene / 3 h / 0 - 70 °C
5.1: Grubbs catalyst first generation / dichloromethane / 2 h / 20 °C
5.2: 12 h / 20 °C
With
Grubbs catalyst first generation; tetrachloromethane; 1-methylcyclohex-1-ene; TOP; sodium hydride; 2,3-dicyano-5,6-dichloro-p-benzoquinone; lithium hexamethyldisilazane;
In
tetrahydrofuran; dichloromethane; N,N-dimethyl-formamide; toluene;
1.1: Williamson etherification;
DOI:10.3987/COM-10-S(E)76
- Guidance literature:
-
Multi-step reaction with 2 steps
1.1: tetrachloromethane; 1-methylcyclohex-1-ene; TOP / toluene / 3 h / 0 - 70 °C
2.1: Grubbs catalyst first generation / dichloromethane / 2 h / 20 °C
2.2: 12 h / 20 °C
With
Grubbs catalyst first generation; tetrachloromethane; 1-methylcyclohex-1-ene; TOP;
In
dichloromethane; toluene;
DOI:10.3987/COM-10-S(E)76
