3-[4-((2S,3R)-3-[(3S)-3-(acetyloxy)-3-(4-fluorophenyl)propyl]-2-{4-[4-(acetyloxy)-3-hydroxy-3-(hydroxymethyl)butyl]phenyl}-4-oxoazetidin-1-yl)phenyl]propanoic acid

Base Information

• Chemical Name: 3-[4-((2S,3R)-3-[(3S)-3-(acetyloxy)-3-(4-fluorophenyl)propyl]-2-{4-[4-(acetyloxy)-3-hydroxy-3-(hydroxymethyl)butyl]phenyl}-4-oxoazetidin-1-yl)phenyl]propanoic acid
• CAS No.: 1039433-62-9
• Molecular Formula: C₃₆H₄₀FNO₉
• Molecular Weight: 649.713

Synonyms:3-[4-((2S,3R)-3-[(3S)-3-(acetyloxy)-3-(4-fluorophenyl)propyl]-2-{4-[4-(acetyloxy)-3-hydroxy-3-(hydroxymethyl)butyl]phenyl}-4-oxoazetidin-1-yl)phenyl]propanoic acid

Chemical Property of 3-[4-((2S,3R)-3-[(3S)-3-(acetyloxy)-3-(4-fluorophenyl)propyl]-2-{4-[4-(acetyloxy)-3-hydroxy-3-(hydroxymethyl)butyl]phenyl}-4-oxoazetidin-1-yl)phenyl]propanoic acid

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Technology Process of 3-[4-((2S,3R)-3-[(3S)-3-(acetyloxy)-3-(4-fluorophenyl)propyl]-2-{4-[4-(acetyloxy)-3-hydroxy-3-(hydroxymethyl)butyl]phenyl}-4-oxoazetidin-1-yl)phenyl]propanoic acid

There total 1 articles about 3-[4-((2S,3R)-3-[(3S)-3-(acetyloxy)-3-(4-fluorophenyl)propyl]-2-{4-[4-(acetyloxy)-3-hydroxy-3-(hydroxymethyl)butyl]phenyl}-4-oxoazetidin-1-yl)phenyl]propanoic acid which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

4-(4-{(2S,3R)-3-[(3S)-3-(acetoxy)-3-(4-fluorophenyl)propyl]-1-[4-(3,3-dihydroxypropyl)phenyl]-4-oxoazetidin-2-yl}phenyl)-2-hydroxy-2-(hydroxymethyl)butyl acetate (1039433-60-7) → 3-[4-((2S,3R)-3-[(3S)-3-(acetyloxy)-3-(4-fluorophenyl)propyl]-2-{4-[4-(acetyloxy)-3-hydroxy-3-(hydroxymethyl)butyl]phenyl}-4-oxoazetidin-1-yl)phenyl]propanoic acid (1039433-62-9)

Guidance literature:

With sodium chlorite; aminosulfonic acid; In tetrahydrofuran; water; at 20 ℃; for 0.333333h;

Reference yield:

3-[4-((2S,3R)-3-[(3S)-3-(acetyloxy)-3-(4-fluorophenyl)propyl]-2-{4-[4-(acetyloxy)-3-hydroxy-3-(hydroxymethyl)butyl]phenyl}-4-oxoazetidin-1-yl)phenyl]propanoic acid (1039433-62-9) → 3-(4-{(2S,3R)-2-{4-[3,4-dihyvdroxy-3-(hydroxymethyl)butyl]phenyl}-3-[(3S)-3-(4-fluorophenyl)-3-hydroxypropyl]-4-oxoazetidin-1-yl}phenyl)propanoic acid (1039433-59-4)

Guidance literature:

With potassium cyanide; In ethanol; for 4h;

upstream raw materials:

4-(4-{(2S,3R)-3-[(3S)-3-(acetoxy)-3-(4-fluorophenyl)propyl]-1-[4-(3,3-dihydroxypropyl)phenyl]-4-oxoazetidin-2-yl}phenyl)-2-hydroxy-2-(hydroxymethyl)butyl acetate

Downstream raw materials:

3-(4-{(2S,3R)-2-{4-[3,4-dihyvdroxy-3-(hydroxymethyl)butyl]phenyl}-3-[(3S)-3-(4-fluorophenyl)-3-hydroxypropyl]-4-oxoazetidin-1-yl}phenyl)propanoic acid

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