4-(4-{(2S,3R)-3-[(3S)-3-(acetoxy)-3-(4-fluorophenyl)propyl]-1-[4-(3,3-dihydroxypropyl)phenyl]-4-oxoazetidin-2-yl}phenyl)-2-hydroxy-2-(hydroxymethyl)butyl acetate

Base Information

• Chemical Name: 4-(4-{(2S,3R)-3-[(3S)-3-(acetoxy)-3-(4-fluorophenyl)propyl]-1-[4-(3,3-dihydroxypropyl)phenyl]-4-oxoazetidin-2-yl}phenyl)-2-hydroxy-2-(hydroxymethyl)butyl acetate
• CAS No.: 1039433-60-7
• Molecular Formula: C₃₆H₄₂FNO₉
• Molecular Weight: 651.729

Synonyms:4-(4-{(2S,3R)-3-[(3S)-3-(acetoxy)-3-(4-fluorophenyl)propyl]-1-[4-(3,3-dihydroxypropyl)phenyl]-4-oxoazetidin-2-yl}phenyl)-2-hydroxy-2-(hydroxymethyl)butyl acetate

Chemical Property of 4-(4-{(2S,3R)-3-[(3S)-3-(acetoxy)-3-(4-fluorophenyl)propyl]-1-[4-(3,3-dihydroxypropyl)phenyl]-4-oxoazetidin-2-yl}phenyl)-2-hydroxy-2-(hydroxymethyl)butyl acetate

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Technology Process of 4-(4-{(2S,3R)-3-[(3S)-3-(acetoxy)-3-(4-fluorophenyl)propyl]-1-[4-(3,3-dihydroxypropyl)phenyl]-4-oxoazetidin-2-yl}phenyl)-2-hydroxy-2-(hydroxymethyl)butyl acetate

There total 1 articles about 4-(4-{(2S,3R)-3-[(3S)-3-(acetoxy)-3-(4-fluorophenyl)propyl]-1-[4-(3,3-dihydroxypropyl)phenyl]-4-oxoazetidin-2-yl}phenyl)-2-hydroxy-2-(hydroxymethyl)butyl acetate which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

(1S)-3-{(2S,3R)-2-(4-{2-[5-(acetyloxy)-2,2-dimethyl-1,3-dioxan-5-yl]ethyl}phenyl)-1-[4-(3,3-diethoxypropyl)phenyl]-4-oxoazetidin-3-yl}-1-(4-fluorophenyl)propyl acetate (1039433-56-1) → 4-(4-{(2S,3R)-3-[(3S)-3-(acetoxy)-3-(4-fluorophenyl)propyl]-1-[4-(3,3-dihydroxypropyl)phenyl]-4-oxoazetidin-2-yl}phenyl)-2-hydroxy-2-(hydroxymethyl)butyl acetate (1039433-60-7)

Guidance literature:

With water; trifluoroacetic acid; In tetrahydrofuran; at 20 ℃; for 16h;

Reference yield:

4-(4-{(2S,3R)-3-[(3S)-3-(acetoxy)-3-(4-fluorophenyl)propyl]-1-[4-(3,3-dihydroxypropyl)phenyl]-4-oxoazetidin-2-yl}phenyl)-2-hydroxy-2-(hydroxymethyl)butyl acetate (1039433-60-7) → 3-[4-((2S,3R)-3-[(3S)-3-(acetyloxy)-3-(4-fluorophenyl)propyl]-2-{4-[4-(acetyloxy)-3-hydroxy-3-(hydroxymethyl)butyl]phenyl}-4-oxoazetidin-1-yl)phenyl]propanoic acid (1039433-62-9)

Guidance literature:

With sodium chlorite; aminosulfonic acid; In tetrahydrofuran; water; at 20 ℃; for 0.333333h;

upstream raw materials:

(1S)-3-{(2S,3R)-2-(4-{2-[5-(acetyloxy)-2,2-dimethyl-1,3-dioxan-5-yl]ethyl}phenyl)-1-[4-(3,3-diethoxypropyl)phenyl]-4-oxoazetidin-3-yl}-1-(4-fluorophenyl)propyl acetate

Downstream raw materials:

3-[4-((2S,3R)-3-[(3S)-3-(acetyloxy)-3-(4-fluorophenyl)propyl]-2-{4-[4-(acetyloxy)-3-hydroxy-3-(hydroxymethyl)butyl]phenyl}-4-oxoazetidin-1-yl)phenyl]propanoic acid

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