(2R)-N-hydroxy-2-methyl-2-(methylsulfonyl)-4-[2-oxo-4-(2-phenylethyl)pyridin-1(2H)-yl]butanamide

Base Information

Chemical Name:(2R)-N-hydroxy-2-methyl-2-(methylsulfonyl)-4-[2-oxo-4-(2-phenylethyl)pyridin-1(2H)-yl]butanamide
CAS No.:1312473-40-7
Molecular Formula:C₁₉H₂₄N₂O₅S
Molecular Weight:392.476
Hs Code.:

Synonyms:(2R)-N-hydroxy-2-methyl-2-(methylsulfonyl)-4-[2-oxo-4-(2-phenylethyl)pyridin-1(2H)-yl]butanamide

Suppliers and Price of (2R)-N-hydroxy-2-methyl-2-(methylsulfonyl)-4-[2-oxo-4-(2-phenylethyl)pyridin-1(2H)-yl]butanamide

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

Total 0 raw suppliers

Chemical Property of (2R)-N-hydroxy-2-methyl-2-(methylsulfonyl)-4-[2-oxo-4-(2-phenylethyl)pyridin-1(2H)-yl]butanamide

Chemical Property:

Purity/Quality:

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:

Useful:

Technology Process of (2R)-N-hydroxy-2-methyl-2-(methylsulfonyl)-4-[2-oxo-4-(2-phenylethyl)pyridin-1(2H)-yl]butanamide

There total 11 articles about (2R)-N-hydroxy-2-methyl-2-(methylsulfonyl)-4-[2-oxo-4-(2-phenylethyl)pyridin-1(2H)-yl]butanamide which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 70.0%

: 1312478-66-2
(2R)-2-methyl-2-(methylsulfonyl)-4-{2-oxo-4-(2-phenylethyl)pyridin-1(2H)-yl}-N-(tetrahydro-2H-pyran-2-yloxy)butanamide

: 1312473-40-7
(2R)-N-hydroxy-2-methyl-2-(methylsulfonyl)-4-[2-oxo-4-(2-phenylethyl)pyridin-1(2H)-yl]butanamide

Guidance literature:: With hydrogenchloride; In 1,4-dioxane; methanol; dichloromethane; for 2h;

Reference yield:

: 1312478-59-3
(2R)-4-(4-iodo-2-oxopyridin-1(2H)-yl)-2-methyl-2-(methylsulfonyl)butanoic acid

: 1312473-40-7
(2R)-N-hydroxy-2-methyl-2-(methylsulfonyl)-4-[2-oxo-4-(2-phenylethyl)pyridin-1(2H)-yl]butanamide

Guidance literature:: Multi-step reaction with 4 steps

1: triethylamine; 1-ethyl-(3-(3-dimethylamino)propyl)-carbodiimide hydrochloride; benzotriazol-1-ol / dichloromethane / 20 - 25 °C

2: potassium carbonate / Pd EnCat_.(TM). / 1,4-dioxane; water / 80 °C

3: cyclohexa-1,4-diene / ethanol / 72 h / 20 - 25 °C / Inert atmosphere

4: hydrogenchloride / dichloromethane; 1,4-dioxane; methanol / 2 h

With hydrogenchloride; cyclohexa-1,4-diene; potassium carbonate; benzotriazol-1-ol; 1-ethyl-(3-(3-dimethylamino)propyl)-carbodiimide hydrochloride; triethylamine; Pd EnCat; In 1,4-dioxane; methanol; ethanol; dichloromethane; water;

Reference yield:

: 1312478-57-1
(2R)-4-(4-iodo-2-oxopyridin-1(2H)-yl)-2-methyl-2-(methylsulfonyl)-N-(tetrahydro-2H-pyran-2-yloxy)butanamide

: 1312473-40-7
(2R)-N-hydroxy-2-methyl-2-(methylsulfonyl)-4-[2-oxo-4-(2-phenylethyl)pyridin-1(2H)-yl]butanamide

Guidance literature:: Multi-step reaction with 3 steps

1: potassium carbonate / Pd EnCat_.(TM). / 1,4-dioxane; water / 80 °C

2: cyclohexa-1,4-diene / ethanol / 72 h / 20 - 25 °C / Inert atmosphere

3: hydrogenchloride / dichloromethane; 1,4-dioxane; methanol / 2 h

With hydrogenchloride; cyclohexa-1,4-diene; potassium carbonate; Pd EnCat; In 1,4-dioxane; methanol; ethanol; dichloromethane; water;