7α-benzyloxymethyl-9-methyl-6β-(2'-phenylindol-3'-yl)-5-tosyl-5,6α,6aβ,7β,8,10aβ-hexahydroindeno<2,1-b>indole

Base Information

Chemical Name:7α-benzyloxymethyl-9-methyl-6β-(2'-phenylindol-3'-yl)-5-tosyl-5,6α,6aβ,7β,8,10aβ-hexahydroindeno<2,1-b>indole
CAS No.:142502-18-9
Molecular Formula:C₄₅H₄₀N₂O₃S
Molecular Weight:688.89
Hs Code.:

Synonyms:7α-benzyloxymethyl-9-methyl-6β-(2'-phenylindol-3'-yl)-5-tosyl-5,6α,6aβ,7β,8,10aβ-hexahydroindeno<2,1-b>indole

Suppliers and Price of 7α-benzyloxymethyl-9-methyl-6β-(2'-phenylindol-3'-yl)-5-tosyl-5,6α,6aβ,7β,8,10aβ-hexahydroindeno<2,1-b>indole

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

Total 0 raw suppliers

Chemical Property of 7α-benzyloxymethyl-9-methyl-6β-(2'-phenylindol-3'-yl)-5-tosyl-5,6α,6aβ,7β,8,10aβ-hexahydroindeno<2,1-b>indole

Chemical Property:

Purity/Quality:

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:

Useful:

Technology Process of 7α-benzyloxymethyl-9-methyl-6β-(2'-phenylindol-3'-yl)-5-tosyl-5,6α,6aβ,7β,8,10aβ-hexahydroindeno<2,1-b>indole

There total 4 articles about 7α-benzyloxymethyl-9-methyl-6β-(2'-phenylindol-3'-yl)-5-tosyl-5,6α,6aβ,7β,8,10aβ-hexahydroindeno<2,1-b>indole which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 88.0%

: 948-65-2
2-phenyl-indole

: 142502-14-5
7α-benzyloxymethyl-6α-hydroxy-9-methyl-5-tosyl-5,6β,6aβ,7β,8,10aβ-hexahydroindeno<2,1-b>indole

: 142502-18-9
7α-benzyloxymethyl-9-methyl-6β-(2'-phenylindol-3'-yl)-5-tosyl-5,6α,6aβ,7β,8,10aβ-hexahydroindeno<2,1-b>indole

Guidance literature:: With boron trifluoride diethyl etherate; In tetrahydrofuran; for 4h; Ambient temperature;
DOI:10.1016/0223-5234(92)90100-F

Reference yield:

: 100-39-0
benzyl bromide

: 142502-18-9
7α-benzyloxymethyl-9-methyl-6β-(2'-phenylindol-3'-yl)-5-tosyl-5,6α,6aβ,7β,8,10aβ-hexahydroindeno<2,1-b>indole

Guidance literature:: Multi-step reaction with 2 steps

1: 99 percent / n-Bu₄NHSO₄, 50percent NaOH / benzene / 0.5 h / Ambient temperature

2: 88 percent / BF₃*Et₂O / tetrahydrofuran / 4 h / Ambient temperature

With sodium hydroxide; boron trifluoride diethyl etherate; tetra(n-butyl)ammonium hydrogensulfate; In tetrahydrofuran; benzene;
DOI:10.1016/0223-5234(92)90100-F

Reference yield:

: 142502-13-4
6α-hydroxy-7α-hydroxymethyl-9-methyl-5-tosyl-5,6β,6aβ,7β,8,10aβ-hexahydroindeno<2,1-b>indole

: 142502-18-9
7α-benzyloxymethyl-9-methyl-6β-(2'-phenylindol-3'-yl)-5-tosyl-5,6α,6aβ,7β,8,10aβ-hexahydroindeno<2,1-b>indole

Guidance literature:: Multi-step reaction with 2 steps

1: 99 percent / n-Bu₄NHSO₄, 50percent NaOH / benzene / 0.5 h / Ambient temperature

2: 88 percent / BF₃*Et₂O / tetrahydrofuran / 4 h / Ambient temperature

With sodium hydroxide; boron trifluoride diethyl etherate; tetra(n-butyl)ammonium hydrogensulfate; In tetrahydrofuran; benzene;
DOI:10.1016/0223-5234(92)90100-F