2-Chloro-5-phenyl-1H-benzoimidazole

Base Information Edit

Chemical Name:2-Chloro-5-phenyl-1H-benzoimidazole
CAS No.:863222-23-5
Molecular Formula:C₁₃H₉ClN₂
Molecular Weight:228.681
Hs Code.:
DSSTox Substance ID:DTXSID701297075
Mol file:863222-23-5.mol

Synonyms:863222-23-5;2-chloro-6-phenyl-1H-benzo[d]imidazole;1H-BENZIMIDAZOLE,2-CHLORO-5-PHENYL-;2-Chloro-5-phenyl-1H-benzoimidazole;2-Chloro-5-phenylbenzimidazole;SCHEMBL2878855;YKTKLYZAFCNQSY-UHFFFAOYSA-N;DTXSID701297075;2-chloro-6-phenyl-1H-benzimidazole

Suppliers and Price of 2-Chloro-5-phenyl-1H-benzoimidazole

Supply Marketing:Edit

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

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Chemical Property of 2-Chloro-5-phenyl-1H-benzoimidazole Edit

Chemical Property:

XLogP3:4.1
Hydrogen Bond Donor Count:1
Hydrogen Bond Acceptor Count:1
Rotatable Bond Count:1
Exact Mass:228.0454260
Heavy Atom Count:16
Complexity:240

Purity/Quality:

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:

Useful:

Canonical SMILES:C1=CC=C(C=C1)C2=CC3=C(C=C2)N=C(N3)Cl

Technology Process of 2-Chloro-5-phenyl-1H-benzoimidazole

There total 3 articles about 2-Chloro-5-phenyl-1H-benzoimidazole which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 73.0%

: 256518-97-5
2-chloro-6-iodo-1H-benzimidazole

: 98-80-6
phenylboronic acid

: 863222-23-5
2-chloro-5-phenylbenzimidazole

Guidance literature:: With tetrakis(triphenylphosphine) palladium⁽⁰⁾; potassium carbonate; In ethanol; water; toluene; at 120 ℃; for 3h; Inert atmosphere;

Reference yield:

: 100381-95-1
5-phenyl-1H-benzo[d]imidazol-2(3H)-one

: 863222-23-5
2-chloro-5-phenylbenzimidazole

Guidance literature:: With N,N-dimethyl-aniline; trichlorophosphate; at 110 ℃;
DOI:10.1016/j.bmcl.2008.08.018

Reference yield:

: 4458-39-3
biphenyl-3,4-diamine

: 863222-23-5
2-chloro-5-phenylbenzimidazole

Guidance literature:: Multi-step reaction with 2 steps

1: tetrahydrofuran; dichloromethane / 6.5 h / 20 °C

2: trichlorophosphate / 1.5 h / 95 °C

With trichlorophosphate; In tetrahydrofuran; dichloromethane;
DOI:10.1016/j.bmcl.2014.01.008