methylthiophosphonic acid O-butyl-O-(3-diphenylthiophosphoryl)phenyl ester

Base Information

• Chemical Name: methylthiophosphonic acid O-butyl-O-(3-diphenylthiophosphoryl)phenyl ester
• CAS No.: 1198151-82-4
• Molecular Formula: C₂₃H₂₆O₂P₂S₂
• Molecular Weight: 460.538
• Mol file: 1198151-82-4.mol

Synonyms:methylthiophosphonic acid O-butyl-O-(3-diphenylthiophosphoryl)phenyl ester

Chemical Property of methylthiophosphonic acid O-butyl-O-(3-diphenylthiophosphoryl)phenyl ester

Chemical Property:

Purity/Quality:

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

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Technology Process of methylthiophosphonic acid O-butyl-O-(3-diphenylthiophosphoryl)phenyl ester

There total 5 articles about methylthiophosphonic acid O-butyl-O-(3-diphenylthiophosphoryl)phenyl ester which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 93.0%

m-hydroxyphenyl(diphenyl)phosphine sulfide (32341-36-9) + Me(BuO)P(S)Cl (18005-38-4) → methylthiophosphonic acid O-butyl-O-(3-diphenylthiophosphoryl)phenyl ester (1198151-82-4)

Guidance literature:

With triethylamine; In benzene; for 12h; Reflux;

DOI:10.1039/b907644a

Reference yield:

3-methoxyphenyl bromide (2398-37-0) → methylthiophosphonic acid O-butyl-O-(3-diphenylthiophosphoryl)phenyl ester (1198151-82-4)

Guidance literature:

Multi-step reaction with 4 steps

1.1: magnesium / tetrahydrofuran / 0 - 5 °C / Inert atmosphere

1.2: 2 h / 50 - 55 °C / Inert atmosphere

2.1: sulfur / benzene / 72 h

3.1: pyridine hydrochloride / 5 h / 180 - 190 °C

4.1: triethylamine / benzene / 12 h / Reflux

With pyridine hydrochloride; sulfur; magnesium; triethylamine; In tetrahydrofuran; benzene;

DOI:10.1039/b907644a

Reference yield:

chloro-diphenylphosphine (1079-66-9,74391-44-9) → methylthiophosphonic acid O-butyl-O-(3-diphenylthiophosphoryl)phenyl ester (1198151-82-4)

Guidance literature:

Multi-step reaction with 4 steps

1.1: magnesium / tetrahydrofuran / 0 - 5 °C / Inert atmosphere

1.2: 2 h / 50 - 55 °C / Inert atmosphere

2.1: sulfur / benzene / 72 h

3.1: pyridine hydrochloride / 5 h / 180 - 190 °C

4.1: triethylamine / benzene / 12 h / Reflux

With pyridine hydrochloride; sulfur; magnesium; triethylamine; In tetrahydrofuran; benzene;

DOI:10.1039/b907644a

upstream raw materials:

3-methoxyphenyl bromide

(3-methoxyphenyl)(diphenyl)phosphane

m-hydroxyphenyl(diphenyl)phosphine sulfide

Me(BuO)P(S)Cl

Downstream raw materials:

[2-([butoxy(methyl)thiophosphoryl]oxy)-6-(diphenylthiophosphoryl)phenyl]-palladium chloride