trans-(4-Amino-1-benzylpyrrolidin-3-yl)-acetic acid ethyl ester

Base Information

Chemical Name:trans-(4-Amino-1-benzylpyrrolidin-3-yl)-acetic acid ethyl ester
CAS No.:144017-84-5
Molecular Formula:C15H22 N2 O2
Molecular Weight:262.352
Hs Code.:
Mol file:144017-84-5.mol

Synonyms:3-Pyrrolidineaceticacid, 4-amino-1-(phenylmethyl)-, ethyl ester, trans-; trans-4-Amino-1-(phenylmethyl)-3-pyrrolidineaceticacid ethyl ester; trans-4-Amino-1-(phenylmethyl)-3-pyrrolidineethanoic acidethyl ester

Suppliers and Price of trans-(4-Amino-1-benzylpyrrolidin-3-yl)-acetic acid ethyl ester

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

American Custom Chemicals Corporation
TRANS-(4-AMINO-1-BENZYLPYRROLIDIN-3-YL)-ACETIC ACID ETHYL ESTER 95.00%
5MG
$ 501.01

Total 2 raw suppliers

Chemical Property of trans-(4-Amino-1-benzylpyrrolidin-3-yl)-acetic acid ethyl ester

Chemical Property:

Vapor Pressure:3.33E-05mmHg at 25°C
Refractive Index:1.539
Boiling Point:354.5°Cat760mmHg
PKA:9.47±0.40(Predicted)
Flash Point:168.2°C
PSA：55.56000
Density:1.094g/cm³
LogP:2.03710

Purity/Quality:

97% ^*data from raw suppliers

TRANS-(4-AMINO-1-BENZYLPYRROLIDIN-3-YL)-ACETIC ACID ETHYL ESTER 95.00% ^*data from reagent suppliers

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:: SDS file from LookChem

Useful:

Technology Process of trans-(4-Amino-1-benzylpyrrolidin-3-yl)-acetic acid ethyl ester

There total 5 articles about trans-(4-Amino-1-benzylpyrrolidin-3-yl)-acetic acid ethyl ester which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 100.0%

: 129975-13-9
trans-4-nitro-1-(phenylmethyl)-3-pyrrolidineacetic acid ethyl ester

: 144017-84-5
trans-4-amino-1-(phenylmethyl)-3-pyrrolidineacetic acid ethyl ester

Guidance literature:: With hydrogen; RaNi; In ethanol; at 20 ℃; for 4h; under 2378.94 Torr;

Reference yield:

: 37746-78-4
4-bromo-trans-crotonic acid ethyl ester

: 144017-84-5
trans-4-amino-1-(phenylmethyl)-3-pyrrolidineacetic acid ethyl ester

Guidance literature:: Multi-step reaction with 3 steps

1: CH₂Cl₂ / 4 h

2: 65 percent / ethanol / 20 °C

3: 84 percent / Raney nickel; H₂ / ethanol / 4 h / 20 °C

With hydrogen; nickel; In ethanol; dichloromethane;
DOI:10.1016/j.bmc.2006.09.019

Reference yield:

: 129975-11-7,131489-60-6
ethyl (E)-4-benzylaminocrotonate

: 144017-84-5
trans-4-amino-1-(phenylmethyl)-3-pyrrolidineacetic acid ethyl ester

Guidance literature:: Multi-step reaction with 2 steps

1: 65 percent / ethanol / 20 °C

2: 84 percent / Raney nickel; H₂ / ethanol / 4 h / 20 °C

With hydrogen; nickel; In ethanol;
DOI:10.1016/j.bmc.2006.09.019